This textbook and all of our professional accomplishments would not be possible without the enduring support of our families. We dedicate this effort to our understanding spouses, Scott, Michelle, and Cathy; our high-spirited children, Matthew and Jocelyn Karlan, Jackson, Chloe, and Haley Bristow, Jason, Lucas, and Evan Li; and to our loving parents, Beverly and Stanley Young, Lynn and Lonnie Bristow, and Chien and Marian Li, who raised us with passions for caring and eternal learning. Our many teachers and mentors provided us with the knowledge and skills to care for women with gynecologic cancers and motivated us to continue pushing the therapeutic envelope until cures are within our grasp. Our colleagues—physicians, scientists, nurses, and other professionals—work shoulder to shoulder with us, and support, challenge, motivate, and make us laugh when it is most needed. And most importantly, this book is dedicated to the legions of women with gynecologic cancer, both living and in our memories, who have taught us tenacity, selflessness, and courage. We hope that this text will educate future generations of clinicians and scientists whom we can enlist on our journey to end cancer as a threat to women.