Gaucher cells in Gaucher disease. The two macrophages are engorged with glucocerebroside as a result of the inherited absence of glucocerebrosidase, required for glycolipid degradation.
Gaucher cell. Marrow film. Large macrophage with gray-blue stained, striated cytoplasm. The lack of the enzyme glucocerebrosidase results in an inability to metabolize glycolipids normally with a resultant accumulation of glucocerebroside in macrophages.
V.H.003 Gaucher Cells. Spleen Imprint
Gaucher cells. Spleen Imprint. (A) Numerous macrophages with gray-blue stained, striated cytoplasm. The lack of the enzyme glucocerebrosidase results in an inability to metabolize glycolipids normally with a resultant accumulation of glucocerebroside in macrophages. Splenic enlargement as a result is common. (B) Periodic acid Schiff stain imparts characteristic reddish-pink coloration to the cytoplasm of Gaucher cells.
V.H.004 Macrophage, Cystine Crystals
Macrophage with cystine crystals. Marrow film. Macrophage engorged with cystine crystals in a case of cystinosis.
V.H.005 Macrophages with Cystine Crystals
Macrophages with cystine crystals. Marrow section. Case of cystinosis with macrophages engorged with cystine crystals.
V.H.006 Macrophages with Cystine Crystals
Macrophages with Cystine Crystals. Marrow films. (A, B) Case of cystinosis with macrophages engorged with cystine crystals. (A) Lower magnification of two crystal engorged macrophages. (B) Higher magnification of macrophage engorged with cystine crystals.
V.H.007 Macrophage, Erythroid Islet
Macrophage, erythroid islet. Marrow film. Macrophage with ingested erythrocytes and surrounding erythroblasts.
V.H.008 Macrophage, Erythrophagocytosis
Macrophage, erythrophagocytosis. Marrow film. Erythrophagocytosis. Note pale erythrocyte and erythrocyte ghost (hemolyzed) in macrophage cytoplasm (arrows).
V.H.009 Macrophage, Erythrophagocytosis
Macrophage, erythrophagocytosis. Marrow film. Erythrophagocytosis. Note pale erythrocyte and numerous shrunken erythrocyte ghosts (hemolyzed) in macrophage cytoplasm. Cytoplasm intensely vacuolated and several apparent nuclear vacuoles.
V.H.010 Macrophage, Erythrophagocytosis
Macrophage, erythrophagocytosis. Marrow film. Two macrophages. One containing numerous presumptive iron particles. The other macrophage has ingested several erythrocytes and ...
Log In to View More
If your institution is currently a subscriber
of the HemOnc Collection please sign in below.
If your institution is not a subscriber
please click here
to learn more.
Want remote access to your institution's subscription?
Sign in to your MyAccess profile while you are actively authenticated on this site via your institution (you will be able to verify this by looking at the top right corner of the screen - if you see your institution's name, you are authenticated). Once logged in to your MyAccess profile, you will be able to access your institution's subscription for 90 days from any location. You must be logged in while authenticated at least once every 90 days to maintain this remote access.
If your institution subscribes to this resource, and you don't have a MyAccess profile, please contact your library's reference desk for information on how to gain access to this resource from off-campus.
Pop-up div Successfully Displayed
This div only appears when the trigger link is hovered over.
Otherwise it is hidden from view.