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VIII.D.001 T(1;19)(q23;p13.3) G-Banding

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Graphic Jump Location

VIII.D.001

t(1;19)(q23;p13.3) G-banding. Arrows indicate sites of translocation.

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VIII.D.002 Dup(1)(q12-21) G-Banding

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Graphic Jump Location

VIII.D.002

dup(1)(q12-21) G-banding. Arrow indicates duplication of chromosome 1.

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VIII.D.003 T(8q24) (MYC gene). FISH

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Graphic Jump Location

VIII.D.003

t(8q24) (MYC gene). FISH. Probe for 3-prime (red) and 5-prime (green) segment of the MYC gene. (A) Normal cell. Two fused signals indicating appropriate juxtaposition of the 3- and 5-prime segments. (B) Abnormal cell. One fused red-green signal (normal chromosome 8). Split red and green signal of the MYC gene, indicating translocation involving chromosome 8 at band q24.

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VIII.D.004 T(4:11)(q21;q23) G-Banding

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Graphic Jump Location

VIII.D.004

t(4:11)(q21;q23) G-banding. Arrows indicate translocation. Note also other abnormalities (e.g. trisomy 20, 22, monosomy 10, lost Y chromosome and derived chromosome (A)).

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VIII.D.005 Del(6)(q15-q22) G-Banding

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Graphic Jump Location

VIII.D.005

del(6)(q15-q22) G-banding. Arrow indicates deletion on long arm of chromosome 6.

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VIII.D.006 I(7)(q10) G-Banding

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Graphic Jump Location

VIII.D.006

i(7)(q10) G-banding. Arrow indicates i7q. Note other abnormalities (e.g. trisomy 1, 3, 6, 15, 17, 19, missing Y, monosomy 13, and other abnormalities (A).

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VIII.D.007 I(7)(q10) FISH

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Graphic Jump Location

VIII.D.007

i(7)(q10) FISH. Probe for the centromere of chromosome 7 (green) and subtelomere of chromosome 7q (red). (A) Normal interphase cell. Two red signals and two green signals. (B) Abnormal interphase cell. Two green signals for two chromosome 7 and three red signals for 7q subtelomere. (C) Abnormal cell with probe for 7p subtelomere (green). Only one signal for 7p noted. The FISH results indicate the presence of two chromosome 7 with three q arms and one p arm, abbreviated i(7)(q10) (interphase preparation).

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VIII.D.008 Trisomy 8 (+8). G-banding

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Graphic Jump Location

VIII.D.008

Trisomy 8 (+8). G-banding. Arrow indicates trisomy 8.

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VIII.D.009 Trisomy 8 (+8). FISH

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Graphic Jump Location

VIII.D.009

Trisomy 8 (+8). FISH. Centromere probe for chromosome 8 (green). Three cells each with trisomy 8(three green signals each) (interphase preparation).

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VIII.D.010 T(8;14)(q24;q32) G-Banding

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Graphic Jump Location

VIII.D.010

t(8;14)(q24;q32) G-banding. Arrows indicate chromosomes 8 and 14 involved in the translocation.

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