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VIII.E.001 Del(11)(q23) G-Banding

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Graphic Jump Location

VIII.E.001

del(11)(q23) G-banding. Arrow indicates foreshortened long arm of chromosome 11.

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VIII.E.002 Del(11)(q23) FISH

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Graphic Jump Location

VIII.E.002

del(11)(q23) FISH. Probe for the MLL gene at 11q23. (A) Normal cell. Two fused signals indicating two chromosomes 11 with intact q23 (interphase preparation). (B) Abnormal cell. Only one fused signal reflecting deleted portion of long arm containing 11(q23) on the abnormal chromosome 11 (interphase preparation).

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VIII.E.003 T(11;14)(q13;q32) G-Banding

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Graphic Jump Location

VIII.E.003

t(11;14)(q13;q32) G-banding. Arrows indicate sites of reciprocal translocation.

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VIII.E.004 T(11;14)(q13;q32) FISH

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Graphic Jump Location

VIII.E.004

t(11;14)(q13;q32) FISH. Probes for IgH (red signal) on chromosome 14q32 and the CCND1 gene on chromosome 11q13. (A) Normal cell. Two red and two green signals (interphase preparation). (B) Two abnormal cells. Each with one red and one green signal representing normal chromosomes 11 and 14 and each with two fused signals representing the reciprocal translocation (interphase preparation).

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VIII.E.005 Del(12)(p11.2) G-Banding

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Graphic Jump Location

VIII.E.005

del(12)(p11.2) G-banding. Arrow indicates chromosome v12 with foreshortened short arm.

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VIII.E.006 Trisomy 12 (+12) G-Banding

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Graphic Jump Location

VIII.E.006

trisomy 12 (+12) G-banding. Arrow indicates trisomy 12. Note also trisomy 22.

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VIII.E.007 Trisomy 12 (+12) FISH

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Graphic Jump Location

VIII.E.007

trisomy 12 (+12) FISH. Probe for centromere on chromosome 12. (A) Normal cell. Two green signals (interphase preparation). (B) Abnormal cell. Three green signals indicating trisomy 12 (interphase preparation).

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VIII.E.008 Del(13)(q14) G-Banding

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Graphic Jump Location

VIII.E.008

del(13)(q14) G-banding. Arrow indicates involved chromosome.

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VIII.E.009 Del(13)(q14) FISH

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Graphic Jump Location

VIII.E.009

del(13)(q14) FISH. Probe for the RB-1 gene on 13(q14) (red signal). (A) Normal cell with two red signals. (B) Abnormal cell with one red signal reflecting deletion of 13(q14) on the abnormal chromosome 13 (interphase preparation).

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VIII.E.010 Del(13)(q14) FISH

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Graphic Jump Location

VIII.E.010

del(13)(q14) FISH. Probe for the RB-1 gene on 13(q14) (red signal). (A) Normal cell with two red signals. (B) Abnormal cell with one red signal reflecting deletion of 13(q14) on the abnormal chromosome 13 (interphase preparation).

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VIII.E.011 T(14)(q32) ...

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