Skip to Main Content


X.K.001 Leukocyte Alkaline Phosphatase Stain of Neutrophils

Graphic Jump Location


Leukocyte alkaline phosphatase stain of neutrophils. Blood film. Composite of (A) normal neutrophils. Image shows the characteristic range of reaction strength of normal neutrophils from zero to about a score of two out of four. Characteristically the score of each of 100 segmented and band neutrophils is summed to give a total score that might average about 80. (B) Segmented and band neutrophils in chronic myelogenous leukemia in which the neutrophilic cells are very weakly positive or negative. In this image the band and segmented neutrophils score zero out of four and the total score would be very low, characteristic of chronic myelogenous leukemia. The availability of measurements of the Ph chromosome and BCR-ABL in CML and other specific markers in diseases in which the leukocyte alkaline phosphatase is altered has made this measurement obsolete in most laboratories. (C) Reactive neutrophilia in which the alkaline phosphatase reaction is strongly positive. These neutrophils are a score of four out of four. In such a sample, the total score of 100 neutrophils counted would be far above the normal range.

Want remote access to your institution's subscription?

Sign in to your MyAccess profile while you are actively authenticated on this site via your institution (you will be able to verify this by looking at the top right corner of the screen - if you see your institution's name, you are authenticated). Once logged in to your MyAccess profile, you will be able to access your institution's subscription for 90 days from any location. You must be logged in while authenticated at least once every 90 days to maintain this remote access.


About MyAccess

If your institution subscribes to this resource, and you don't have a MyAccess profile, please contact your library's reference desk for information on how to gain access to this resource from off-campus.

Pop-up div Successfully Displayed

This div only appears when the trigger link is hovered over. Otherwise it is hidden from view.