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XII.B.001 Marrow Hematopoietic Cords and Sinuses

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XII.B.001

Marrow Hematopoietic Cords and Sinuses. Rat femoral marrow. The marrow sinuses are exposed in this transected femur and can be seen distributed among the hematopoietic cords containing developing blood cells. Some sinuses are exposed in cross-section and others are exposed, more or less, longitudinally or obliquely. The rat femur has a few fat cells, which when transected are sac-like in appearance (see arrow).(Scanning electron micrograph)

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XII.B.002 Marrow Hematopoietic Cords and Sinuses

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XII.B.002

Marrow Hematopoietic Cords and Sinuses. Rat femoral marrow. Higher magnification than in XII.B.001. The marrow sinuses are exposed in this transected rat femur and can be seen separating the hematopoietic cords containing developing blood cells. Some sinuses are exposed in cross-section and others are exposed, more or less, longitudinally or obliquely. Sinus anastomosis can be seen on the right side of the image. Rat marrow contains a few fat cells, which can be seen as four transected empty sacs, just left of center, running from lower left (arrow) to the top center. The empty spaces in the hematopoietic cords are artifacts from cells dislodged during femoral transection. (Scanning electron micrograph)

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XII.B.003 Marrow Hematopoietic Cords

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XII.B.003

Marrow Hematopoietic Cords. Rat femoral marrow. Higher magnification than in XII.B.002. A few marrow sinuses are exposed in this transected femur and can be seen separating the hematopoietic cords containing developing blood cells. Rat marrow contains a few fat cells, one of which can be seen as a transected empty sac (asterisk) adjacent to a sinus. In the sinus lumen, a worm-like structure is a proplatelet. The transected granular cell adjacent to the fat cell, below and to its right, is a transected megakaryocyte, intimately in contact with the wall of the sinus to its lower left. (Scanning electron micrograph)

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XII.B.004 Yellow Marrow

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XII.B.004

Yellow Marrow. Rat tail vertebra. Here red marrow is converted to yellow marrow (hematopoietically inactive). Note total replacement by fat cells. Yellow marrow can, under prolonged stimulation, revert to hematopoietically active red marrow. In the rat, induction of a hemolytic anemia with a red cell lysing agent can induce restoration of erythropoiesis in the tail vertebra. If a tail vertebra is disarticulated and placed in the rat peritoneal cavity it undergoes, first degeneration, than an ingrowth of vessels, then restitution of hematopoiesis, and then reversion to yellow marrow. (Scanning electron microscopy)

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XII.B.005 Marrow sinus wall

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XII.B.005

Marrow sinus wall. Schematic showing ...

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