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EOSINOPHIL COUNTS

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  • The normal absolute eosinophil count in adults is less than 0.5 × 109 cells/L.

  • The eosinophil count is higher in neonates.

  • Eosinophils are primarily tissue dwelling, with 300 cells in the tissues for every blood eosinophil.

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CAUSES OF EOSINOPHILIA

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  • The degree of eosinophilia is described as:

    — Mild (0.5 to 1.5 × 109 eosinophils/L).

    — Moderate (1.5 to 5.0 × 109 eosinophils/L).

    — Marked (>5.0 × 109 eosinophils/L).

  • The most common causes of eosinophilia include:

    — Worldwide: infections with helminthic parasites.

    — In industrialized countries: asthma and other allergic disorders (drug allergy, allergic rhinitis, atopic dermatitis).

    — Allergic diseases generally result in only mild eosinophilia.

    — The major causes of eosinophilia are listed in Table 34–1.

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Table Graphic Jump Location
TABLE 34–1CAUSES OF AN EOSINOPHILIA

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