Skip to Main Content

++

CLASSIFICATION

++

  • Lymphocyte malignancies comprise a wide spectrum of different morphologic and clinical syndromes.

  • The International Lymphoma Study Group proposed a new classification termed Revised European–American Lymphoma classification, or REAL classification which was modified in 2001 and updated in 2008 by the World Health Organization (WHO) (see Table 54–1).

  • The REAL/WHO classification makes use of the pathologic, immunophenotypic, genetic, and clinical features to define separate disease entities (Table 54–1).

  • Distinctive cytogenetic abnormalities are also described in Table 54–1.

  • Tumors are divided into two categories: indolent versus aggressive (Tables 54–2 and 54–3).

++
Table Graphic Jump Location
TABLE 54–1INDOLENT LYMPHOMAS
++
Table Graphic Jump Location
TABLE 54–2AGGRESSIVE LYMPHOMAS
++
Table Graphic Jump Location
TABLE 54–3CLASSIFICATION OF LYMPHOMA AND LYMPHOID LEUKEMIA BY WORLD HEALTH ORGANIZATION

Pop-up div Successfully Displayed

This div only appears when the trigger link is hovered over. Otherwise it is hidden from view.