TY - CHAP M1 - Book, Section TI - Erythrocyte Membrane Disorders A1 - Lichtman, Marshall A. A1 - Kaushansky, Kenneth A1 - Prchal, Josef T. A1 - Levi, Marcel M. A1 - Burns, Linda J. A1 - Armitage, James O. PY - 2017 T2 - Williams Manual of Hematology, 9e AB - The erythrocyte membrane plays a critical role in the maintenance of the biconcave shape and integrity of the red cell.It provides flexibility, durability, and tensile strength, enabling erythrocytes to undergo extensive and repeated distortion during their passage through the microvasculature.It consists of a lipid bilayer with embedded transmembrane proteins and an underlying membrane protein skeleton that is attached to the bilayer via linker proteins.The integrity of the membrane relies on vertical interactions between the skeleton and the bilayer, as well as on horizontal interactions within the membrane skeletal network. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/04/19 UR - hemonc.mhmedical.com/content.aspx?aid=1133362702 ER -