TY - CHAP M1 - Book, Section TI - Primary Myelofibrosis A1 - Lichtman, Marshall A. A1 - Kaushansky, Kenneth A1 - Kipps, Thomas J. A1 - Prchal, Josef T. A1 - Levi, Marcel M. Y1 - 2011 N1 - T2 - Williams Manual of Hematology, 8e AB - Primary myelofibrosis is a chronic clonal myeloid disorder that originates in mutations in a multipotential hematopoietic cell. The disease is characterized by (a) anemia, (b) splenomegaly, (c) increased CD34+ cells, immature granulocytes, erythroid precursors, and teardrop-shaped red cells in the blood, (d) marrow fibrosis and increased dysmorphic megakaryocytes, and (e) osteosclerosis. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/04/20 UR - hemonc.mhmedical.com/content.aspx?aid=1126652851 ER -