TY - CHAP M1 - Book, Section TI - Cancer and Coagulopathy A1 - Rosovsky, Rachel P.G. A2 - Chabner, Bruce A. A2 - Longo, Dan L. Y1 - 2016 N1 - T2 - Harrison's Manual of Oncology, 2e AB - The association between cancer and thrombosis was first proposed by Armand Trousseau (Figure 19-1) when he recognized the condition of thrombophlebitis migrans, as a forewarning of occult malignancy (1). In 1865, he remarked, "Should you, when in doubt as to the nature of an affection of the stomach, should you when hesitating between chronic gastritis, simple ulcer, and cancer, observe a vein become infected in the arm or leg, you may dispel your doubt, and pronounce in a positive manner that there is a cancer …" (1). Although the association of hemostatic disorders and cancer has been studied extensively over the past 100 years, venous thromboembolism (VTE), defined herein as pulmonary embolus (PE) or deep vein thrombosis (DVT), remains a major cause of morbidity and mortality in cancer patients. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/04/19 UR - hemonc.mhmedical.com/content.aspx?aid=1127647294 ER -