RT Book, Section A1 Hilal-Dandan, Randa A1 Brunton, Laurence L. SR Print(0) ID 1127554459 T1 Antiretroviral Agents and Treatment of HIV Infection T2 Goodman and Gilman's Manual of Pharmacology and Therapeutics, 2e YR 2016 FD 2016 PB McGraw-Hill Education PP New York, NY SN 9780071769174 LK hemonc.mhmedical.com/content.aspx?aid=1127554459 RD 2024/04/19 AB The pharmacotherapy of HIV infection is a rapidly moving field. Three-drug combinations are the minimum standard of care for this infection, so current agents constitute several thousand possible regimens. Knowing the essential features of the pathophysiology of this disease and how chemotherapeutic agents affect the virus and the host is critical in developing a rational approach to therapy. Unique features of this drug class include the need for lifelong administration to control virus replication and the possibility of rapid emergence of permanent drug resistance if these agents are not used properly.