RT Book, Section
A1 Longo, Dan L.
A2 Chabner, Bruce A.
A2 Longo, Dan L.
SR Print(0)
ID 1127646860
T1 Interferons
T2 Harrison's Manual of Oncology, 2e
YR 2016
FD 2016
PB McGraw-Hill Education
PP New York, NY
SN 9780071793254
LK hemonc.mhmedical.com/content.aspx?aid=1127646860
RD 2024/04/19
AB The  interferons  (IFNs)  are  a  family  of  proteins  that  are  grouped  into  three  classes  α,  β,  and  γ.  They  were  discovered  based  on  their  ability  to  "interfere"  with  viral  infection  of  cells.  Subsequent  study  has  revealed  a  panoply  of  biological  actions  including  immunomodulatory,  antiproliferative,  and  antiangiogenic  effects  (1).  Nearly  all  the  oncologic  applications  of  the  IFNs  have  been  of  the  α  class.