RT Book, Section
A1 Fidias, Panos
A2 Chabner, Bruce A.
A2 Longo, Dan L.
SR Print(0)
ID 1127649303
T1 Thymoma
T2 Harrison's Manual of Oncology, 2e
YR 2016
FD 2016
PB McGraw-Hill Education
PP New York, NY
SN 9780071793254
LK hemonc.mhmedical.com/content.aspx?aid=1127649303
RD 2024/04/19
AB Thymoma  is  a  rare  disease,  with  an  incidence  of  only  0.13  per  100,000  person-years  (1).  However,  it  is  the  most  common  tumor  of  the  anterior  mediastinum,  representing  approximately  30%  of  anterior  mediastinal  lesions  and  20%  of  all  mediastinal  tumors  in  adults.  Based  on  Surveillance,  Epidemiology  and  End  Results  (SEER)  data  from  1973  to  2006  the  incidence  is  similar  between  males  and  females.  Interestingly,  the  incidence  in  the  United  States  is  higher  in  African  Americans  and  especially  Asian/Pacific  Islanders  compared  to  whites  or  Hispanics.  The  median  age  at  presentation  is  around  50  years  and  it  peaks  in  the  seventh  decade.  Approximately  one-third  of  patients  are  asymptomatic  at  presentation,  one-third  have  symptoms  from  local  extent  of  their  tumor,  and  one-third  present  with  paraneoplastic  syndromes,  typically  myasthenia  gravis  (MG).