RT Book, Section A1 Motzer, Robert J. A1 Bosl, George J. A2 Longo, Dan L. SR Print(0) ID 1128357464 T1 TESTICULAR CANCER T2 Harrison's Hematology and Oncology, 2e YR 2013 FD 2013 PB McGraw-Hill Education PP New York, NY SN 9780071814904 LK hemonc.mhmedical.com/content.aspx?aid=1128357464 RD 2024/04/25 AB Primary germ cell tumors (GCTs) of the testis arising by the malignant transformation of primordial germ cells constitute 95% of all testicular neoplasms. Infrequently, GCTs arise from an extragonadal site, including the mediastinum; retroperitoneum; and, very rarely, the pineal gland. This disease is notable for the young age of the affected patients, the totipotent capacity for differentiation of the tumor cells, and its curability; approximately 95% of newly diagnosed patients are cured. Experience in the management of GCTs leads to improved outcome.