RT Book, Section
A1 Varadhachary, Gauri R.
A1 Abbruzzese, James L.
A2 Longo, Dan L.
SR Print(0)
ID 1128357872
T1 CARCINOMA OF UNKNOWN PRIMARY
T2 Harrison's Hematology and Oncology, 2e
YR 2013
FD 2013
PB McGraw-Hill Education
PP New York, NY
SN 9780071814904
LK hemonc.mhmedical.com/content.aspx?aid=1128357872
RD 2024/04/19
AB Carcinoma  of  unknown  primary  (CUP)  is  a  biopsy-proven  (mainly  epithelial)  malignancy  for  which  the  anatomic  site  of  origin  remains  unidentified  after  an  intensive  search.  CUP  is  one  of  the  10  most  frequently  diagnosed  cancers  worldwide,  accounting  for  approximately  3–5%  of  all  cancers.  Most  investigators  do  not  include  lymphomas,  metastatic  melanomas,  and  metastatic  sarcomas  that  present  without  a  known  primary  tumor  as  CUP  because  these  cancers  have  specific  stage-  and  histology-based  treatments  that  guide  management.