RT Book, Section A1 Lichtman, Marshall A. A1 Kaushansky, Kenneth A1 Prchal, Josef T. A1 Levi, Marcel M. A1 Burns, Linda J. A1 Armitage, James O. SR Print(0) ID 1133364630 T1 The Mononucleosis Syndromes T2 Williams Manual of Hematology, 9e YR 2017 FD 2017 PB McGraw-Hill Education PP New York, NY SN 9781259642470 LK hemonc.mhmedical.com/content.aspx?aid=1133364630 RD 2024/04/19 AB Infectious mononucleosis is defined as any blood lymphocytosis induced in response to an infectious agent.Usually greater than 50% of the circulating white cells are lymphocytes, more than 10% of which have the morphology of reactive lymphocytes (Figure 52–1).Table 52–1 lists the etiologic agents that produce mononucleosis.Pharyngeal form:— A sore throat is preceded by 1 to 2 weeks of lethargy.— Epstein-Barr virus (EBV) generally is the cause.Glandular form without pharyngitis:— Lymph node enlargement occurs.— The usual cause is agents other than EBV (eg, Toxoplasma gondii).Typhoidal form:— Lethargy with fever or diarrhea without pharyngitis, usually as a consequence of cytomegalovirus (CMV), is characteristic.