RT Book, Section
A1 Lichtman, Marshall A.
A1 Kaushansky, Kenneth
A1 Prchal, Josef T.
A1 Levi, Marcel M.
A1 Burns, Linda J.
A1 Armitage, James O.
SR Print(0)
ID 1133365486
T1 Amyloidosis
T2 Williams Manual of Hematology, 9e
YR 2017
FD 2017
PB McGraw-Hill Education
PP New York, NY
SN 9781259642470
LK hemonc.mhmedical.com/content.aspx?aid=1133365486
RD 2024/04/20
AB Amyloidosis  is  a  heterogeneous  group  of  diseases  characterized  by  tissue  infiltration  with  misfolded  protein  precursors.The  term  amyloid  is  used  to  describe  a  substance  with  a  homogeneous  eosinophilic  appearance  by  light  microscopy,  a  green  birefringence  on  polarizing  light  microscopy,  and  a  characteristic  β-pleated  sheet  appearance  by  x-ray  diffraction.Terms  such  as  primary,  secondary,  senile,  dialysis-associated,  and  myeloma-associated  have  been  abandoned  in  favor  of  the  etiologically  based,  chemical  terminology  (Table  71–1)  (eg,  immunoglobulin  light  chain  amyloidosis  is  termed  AL  amyloidosis).