RT Book, Section A1 Patel, Shreyaskumar R. A1 Benjamin, Robert S. A2 Longo, Dan L. SR Print(0) ID 1135229901 T1 Soft Tissue and Bone Sarcomas and Bone Metastases T2 Harrison's Hematology and Oncology, 3e YR 2016 FD 2016 PB McGraw-Hill Education PP New York, NY SN 9781259835834 LK hemonc.mhmedical.com/content.aspx?aid=1135229901 RD 2024/04/24 AB Sarcomas are rare (<1% of all malignancies) mesenchymal neoplasms that arise in bone and soft tissues. These tumors are usually of mesodermal origin, although a few are derived from neuroectoderm, and they are biologically distinct from the more common epithelial malignancies. Sarcomas affect all age groups; 15% are found in children <15 years of age, and 40% occur after age 55 years. Sarcomas are one of the most common solid tumors of childhood and are the fifth most common cause of cancer deaths in children. Sarcomas may be divided into two groups, those derived from bone and those derived from soft tissues.