RT Book, Section A1 Dineen, Sean A1 Rodriguez-Bigas, Miguel A. A2 Morita, Shane Y. A2 Balch, Charles M. A2 Klimberg, V. Suzanne A2 Pawlik, Timothy M. A2 Posner, Mitchell C. A2 Tanabe, Kenneth K. SR Print(0) ID 1145762134 T1 Colorectal Cancer: Molecular Biology and Inherited Cancer Syndromes T2 Textbook of Complex General Surgical Oncology YR 2018 FD 2018 PB McGraw-Hill Education PP New York, NY SN 9780071793315 LK hemonc.mhmedical.com/content.aspx?aid=1145762134 RD 2024/04/19 AB The treatment of colorectal cancer (CRC) is evolving continuously and many important advances have recently led to improved prognosis. Surgery remains an integral component of multidisciplinary treatment. Targeted therapies are being developed in the laboratory and implemented clinically, thus taking advantage of major advances in understanding the molecular biology of CRC. This chapter briefly reviews the epidemiology of CRC and then the molecular biology of CRC and discusses inherited CRC syndromes, and also CRC screening and surveillance.