RT Book, Section A1 Nadler, Ashlie A1 Swallow, Carol J. A2 Morita, Shane Y. A2 Balch, Charles M. A2 Klimberg, V. Suzanne A2 Pawlik, Timothy M. A2 Posner, Mitchell C. A2 Tanabe, Kenneth K. SR Print(0) ID 1145762824 T1 Recurrent Colorectal Cancer T2 Textbook of Complex General Surgical Oncology YR 2018 FD 2018 PB McGraw-Hill Education PP New York, NY SN 9780071793315 LK hemonc.mhmedical.com/content.aspx?aid=1145762824 RD 2024/04/19 AB Advances in the treatment of primary rectal cancer, including total mesorectal excision (TME) and neoadjuvant chemoradiation, have reduced the local recurrence (LR) rate to approximately 10% in the modern era.1-3 While the LR rate following resection of rectal cancer significantly exceeded that of colon cancer in older publications, the two are now roughly equivalent.4-6 Given the present incidence of colorectal cancer (CRC) in Western countries of approximately 130,000 cases annually,7 the burden of LR nevertheless remains significant.