RT Book, Section
A1 Bunn, H. Franklin
A1 Nathan, David G.
A2 Bunn, H. Franklin
A2 Aster, Jon C.
SR Print(0)
ID 1104131083
T1 Thalassemia
T2 Pathophysiology of Blood Disorders
YR 2011
FD 2011
PB McGraw-Hill Medical
PP New York, NY
SN 9780071713788
LK hemonc.mhmedical.com/content.aspx?aid=1104131083
RD 2024/04/19
AB LEARNING  OBJECTIVESAfter  studying  this  chapter  you  should  be  able  to:Outline  the  changes  in  globin  gene  expression  that  occur  during  fetal  development.Explain  the  molecular  genetics  and  inheritance  of  alpha  and  beta  thalassemias.Grasp  the  cellular  pathogenesis  of  alpha  and  beta  thalassemias.Describe  the  clinical  and  laboratory  features  of  beta  thalassemia  minor  (trait)  and  beta  thalassemia  major  and  the  different  types  of  alpha  thalassemia.Understand  the  pathophysiologic  principles  underlying  treatment  of  beta  thalassemia  major.