RT Book, Section A1 Brar, Rondeep S. A1 Schrier, Stanley L. A2 Kaushansky, Kenneth A2 Lichtman, Marshall A. A2 Prchal, Josef T. A2 Levi, Marcel M. A2 Press, Oliver W. A2 Burns, Linda J. A2 Caligiuri, Michael SR Print(0) ID 1121088548 T1 Consultative Hematology T2 Williams Hematology, 9e YR 2015 FD 2015 PB McGraw-Hill Education PP New York, NY SN 9780071833004 LK hemonc.mhmedical.com/content.aspx?aid=1121088548 RD 2024/04/18 AB SUMMARYHematology is a unique science in that its complexity is readily accessible via the examination of blood and marrow. The ease with which a complete blood count (CBC) may be obtained also leads to frequent observation of values which fall outside the reference range. Such perturbations may be the sign of something as ominous as acute leukemia, or as inconsequential as the common cold. That such changes might generate considerable anxiety, both for patients and providers, is not surprising given the plethora of life-threatening diseases that often manifest classic CBC findings.This ever-increasing dependence on labs as screening tools generates a seemingly endless supply of “abnormal” results, often triggering hematologic consultation. Electronic medical records (EMRs), as repositories for this ever-growing data, serve as invaluable tools in evaluating the chronicity and trend of such findings.In this chapter, we outline our approach to dealing with these common queries. The individual epidemiology, pathogenesis, and treatment of such disorders are covered comprehensively and with clarity within their corresponding chapters and are not repeated here. Rather, what we describe is our thought process in approaching such questions and narrowing the broad differential to that which is reasonable and probable.