RT Book, Section
A1 Gregg, Xylina T.
A2 Kaushansky, Kenneth
A2 Lichtman, Marshall A.
A2 Prchal, Josef T.
A2 Levi, Marcel M.
A2 Press, Oliver W.
A2 Burns, Linda J.
A2 Caligiuri, Michael
SR Print(0)
ID 1121091974
T1 Erythropoietic Effects of Endocrine Disorders
T2 Williams Hematology, 9e
YR 2015
FD 2015
PB McGraw-Hill Education
PP New York, NY
SN 9780071833004
LK hemonc.mhmedical.com/content.aspx?aid=1121091974
RD 2024/04/25
AB SUMMARYAnemia  is  the  most  common  hematopoietic  abnormality  in  endocrine  disorders  and  may  be  the  first  manifestation  of  an  endocrine  disorder.  Polycythemia/erythrocytosis  is  less  common,  but  occurs  in  certain  endocrine  disorders.  The  pathophysiologic  basis  of  the  anemia  is  often  multifactorial,  but  a  direct  influence  of  hormones  on  erythropoiesis  in  some  instances  may  contribute  to  anemia.  A  decreased  plasma  volume  in  some  of  these  disorders  may  mask  the  severity  of  anemia.  It  has  been  proposed  that  anemia  in  endocrine-deficiency  states  may  be  physiologic  to  adjust  for  decreased  oxygen  requirements.  Some  endocrine  disorders  are  associated  with  an  impaired  response  to  the  therapeutic  use  of  erythropoietin.