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Chapter 41: Guidelines for Chemotherapy Dosage Adjustment

Pamela W. McDevitt; Tito Fojo

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    AMA Citation
    McDevitt PW, Fojo T. McDevitt P.W., Fojo T McDevitt, Pamela W., and Tito Fojo.Guidelines for Chemotherapy Dosage Adjustment. In: Boyiadzis MM, Frame JN, Kohler DR, Fojo T. Boyiadzis M.M., Frame J.N., Kohler D.R., Fojo T Eds. Michael M. Boyiadzis, et al.eds. Hematology-Oncology Therapy, 2e New York, NY: McGraw-Hill; . http://hemonc.mhmedical.com/content.aspx?bookid=1611&sectionid=126669053. Accessed February 18, 2019.
    MLA Citation
    McDevitt PW, Fojo T. McDevitt P.W., Fojo T McDevitt, Pamela W., and Tito Fojo.. "Guidelines for Chemotherapy Dosage Adjustment." Hematology-Oncology Therapy, 2e Boyiadzis MM, Frame JN, Kohler DR, Fojo T. Boyiadzis M.M., Frame J.N., Kohler D.R., Fojo T Eds. Michael M. Boyiadzis, et al. New York, NY: McGraw-Hill, , http://hemonc.mhmedical.com/content.aspx?bookid=1611&sectionid=126669053.

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INTRODUCTION

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Alphabetical Listing of Drugs by both Generic (bold) and Proprietary Names
...
Drug Names: Generic (in bold) or Proprietary Drug Names: Generic (in bold) or Proprietary Adjust if Function Impaired
Hepatic Renal
Abiraterone acetate Zytiga® + −
Abraxane® Paclitaxel protein bound particles + −
Adcetris™ Brentuximab vedotin − −
ado-trastuzumab emtansine Kadcyla™ ± ±
Adriamycin® Doxorubicin HCl + −
Afatinib Gilotrif ± ±
Afatinib dimaleate Gilotrif™ ± ±
Afinitor® Everolimus + ±
Agrylin® Anagrelide HCl + −
Aldesleukin Proleukin® − +
Alemtuzumab Campath® − −
Alimta® Pemetrexed disodium − ±
Alitretinoin Panretin® − −
Alkeran® Melphalan (or Melphalan HCl) − +
Altretamine Hexalen® − −
Amifostine Ethyol® − −
Aminoglutethimide Cytadren® − −
Amsacrine Amsidine® + +
Amsidine® Amsacrine + +
Anagrelide HCl Agrylin® + −
Anastrozole Arimidex® + −
Aranesp® Darbepoetin alfa − −
Aredia® Pamidronate disodium ± +
Arimidex® Anastrozole + −
Aromasin® Exemestane − −
Arranon® Nelarabine ± ±
Arsenic trioxide Trisenox™ + +
Arzerra™ Ofatumumab − −
Asparaginase (E. coli source) Elspar® ± ±
Asparaginase (Erwinia chrysanthemi source) Erwinaze™ ± ±
Atralin™ Tretinoin + +
Avastin® Bevacizumab − −
Axitinib Inlyta® ± ±
Azacitidine Vidaza® + +
Bendamustine HCl Treanda® + +
Bevacizumab Avastin® − −
Bexarotene Targretin® ± ±
Bexxar® Tositumomab − ±
Bicalutamide Casodex® ± −
BiCNU® Carmustine ± +
Blenoxane® Bleomycin sulfate ± +
Bleomycin sulfate Blenoxane® ± +
Bortezomib Velcade® + ±
Bosulif® Bosutinib ± ±
Bosutinib Bosulif® ± ±
Brentuximab vedotin Adcetris™ − −
Buserelin acetate Suprefact® − −
Busulfan Busulfex® ± −
Busulfex® Busulfan ± −
Cabazitaxel Jevtana® ± ±
Cabozantinib S-malate Cometriq™ ± ±
Campath® Alemtuzumab − −
Camptosar® Irinotecan HCl + −
Capecitabine Xeloda® ± +
Caprelsa® Vandetanib ± +
Carboplatin Paraplatin−AQ® − +
Carfilzomib Kyprolis™ ± −
Carmustine BiCNU® ± +
Casodex® Bicalutamide ± −
CeeNU® Lomustine ± +
Cerubidine® Daunorubicin HCl + +
Cetuximab Erbitux® − −
Chlorambucil Leukeran® ± +
Cisplatin Platinol® − +
Cladribine Leustatin® ± +
Clofarabine Clolar® ± ±
Clolar® Clofarabine ± ±
Cometriq™ Cabozantinib S-malate ± ±
Cosmegen® Dactinomycin ± −
Crizotinib Xalkori® ± ±
Cytadren® Aminoglutethimide − −
Cytarabine Cytosar-U® + +
Cytarabine lipid complex (liposome) DepoCyt® − −
Cytosar-U® Cytarabine + +
Dabrafenib Tafinlar ± ±
Dabrafenib mesylate Tafinlar® ± ±
Dacarbazine DTIC-Dome® ± +
Dacogen™ Decitabine ± ±
Dactinomycin Cosmegen® ± −
Denileukin diftitox Ontak® − −
Denosumab Xgeva® ± ±
Darbepoetin alfa Aranesp® − −
Dasatinib Sprycel® ± ±
Daunorubicin HCl Cerubidine® + +

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