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Autoimmune hemolytic anemia (AIHA) is an acquired immunologic disease in which a patient's red blood cells are selectively destroyed or hemolyzed by autoantibodies (auto-Ab) produced by the patient's own immune system
Mack P, Freedman J. Transfus Med Rev 2000;14: 223–233
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Epidemiology
Idiopathic AIHA is more common in women than men (2:1) with a peak incidence in the fourth and fifth decades of life. Idiopathic AIHA is not associated with any demonstrable underlying disease
Secondary causes have been reported in 20–80% of case series