Sections View Full Chapter Figures Tables Videos Annotate Full Chapter Figures Tables Videos Supplementary Content +++ II.G.001 Alder Reilly Anomaly ++ Graphic Jump LocationView Full Size||Download Slide (.ppt) II.G.001 Alder Reilly Anomaly. Blood film. Lymphocyte with large cytoplasmic granules characteristic of the mucopolysacchidoses. +++ II.G.002 Batten Disease ++ Graphic Jump LocationView Full Size||Download Slide (.ppt) II.G.002 Batten disease. (A-D) Lymphocytes displaying small and large vacuoles in cytoplasm. Batten disease is a fatal, inherited disorder of the nervous system that begins in childhood. In some cases, the early signs are subtle, taking the form of personality and behavior changes, slow learning, clumsiness, or stumbling. Symptoms of Batten disease result from accumulation of lipopigments made up of fats and proteins in the tissues. +++ II.G.003 Chediak-Higashi Disease ++ Graphic Jump LocationView Full Size||Download Slide (.ppt) II.G.003 Chediak-Higashi Disease. Blood Film. Large cytoplasmic granule observed in a blood lymphocyte, characteristic of this disorder. +++ II.G.004 Chediak-Higashi Disease ++ Graphic Jump LocationView Full Size||Download Slide (.ppt) II.G.004 Chediak-Higashi Disease. Blood Film. Two nuclei in lymphocyte. Unusual finding. +++ II.G.005 Congenital Rubella ++ Graphic Jump LocationView Full Size||Download Slide (.ppt) II.G.005 Congenital Rubella. Blood films. (A) Large plasmacytoid cell. Small nucleated red cell. (B) Two plasmacytoid cells with intensely blue cytoplasm. +++ II.G.006 Drug reaction ++ Graphic Jump LocationView Full Size||Download Slide (.ppt) II.G.006 Drug reaction. Blood film. Composite of reactive lymphocytes from patients undergoing drug reactions. (A) Large lymphocyte with nucleoli. (B) Large lymphocyte with nucleoli. (C) Lymphocyte with intensely blue cytoplasm (plasmacytoid lymphocyte). +++ II.G.007 Hurler Disease ++ Graphic Jump LocationView Full Size||Download Slide (.ppt) II.G.007 Hurler disease. Blood film. Lymphocyte. Note numerous cytoplasmic granules characteristic of this mucopolysaccharidosis. Presumably these are lysosomal accumulations of glycosaminoglycans, characteristic of this deficiency in enzymes that degrade glycosaminoglycan (α-L-iduronidase in Hurler disease). +++ II.G.008 Infectious Lymphocytosis ++ Graphic Jump LocationView Full Size||Download Slide (.ppt) II.G.008 Infectious lymphocytosis. Blood film. Increased lymphocyte count with small lymphocytes as the characteristic cell. +++ II.G.009 Plasma Cells: Mott Cells ++ Graphic Jump LocationView Full Size||Download Slide (.ppt) II.G.009 Infectious mononucleosis. Blood film. Three large lymphocytes with abundant cytoplasm. Cytoplasmic periphery conforms to red cell outlines. Nuclear shape not a strict circle but elongated or irregular. +++ II.G.010 Plasma Cells: Mott Cells ++ Graphic Jump LocationView Full Size||Download Slide (.ppt) II.G.010 Infectious mononucleosis. Blood film. Four large lymphocytes with abundant cytoplasm. Cytoplasmic periphery conforms to red cell outlines. Nuclear shape not a strict circle but elongated or irregular. +++ II.G.011 Infectious Mononucleosis ++ Graphic Jump LocationView Full Size||... Your Access profile is currently affiliated with [InstitutionA] and is in the process of switching affiliations to [InstitutionB]. Please select how you would like to proceed. Keep the current affiliation with [InstitutionA] and continue with the Access profile sign in process Switch affiliation to [InstitutionB] and continue with the Access profile sign in process Get Free Access Through Your Institution Learn how to see if your library subscribes to McGraw Hill Medical products. Subscribe: Institutional or Individual Sign In Error: Incorrect UserName or Password Username Error: Please enter User Name Password Error: Please enter Password Sign in Forgot Password? Forgot Username? Download the Access App: iOS | Android Sign in via OpenAthens Sign in via Shibboleth You already have access! Please proceed to your institution's subscription. Create a free profile for additional features.