V.I: Lymphocytes and Plasma Cells

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V.I.001

Lymphocyte. Marrow film. This image contains two erythroblasts (late basophilic stage) and seven small lymphocytes with their characteristic extremely high nuclear to cytoplasmic ratio and resulting thin rim of cytoplasm.

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V.I.002

Lymphocyte. Marrow film. This image contains a cluster of eight small lymphocytes and one large lymphocyte. One bare nucleus is amidst the cluster representing a cell smashed during preparation. The small lymphocytes display their characteristic extremely high nuclear to cytoplasmic ratio and resulting thin rim of cytoplasm. A somewhat smudged band neutrophil is in the field.

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V.I.003

Lymphocyte. Marrow film. Three smudge cells probably represent lymphocytes smashed in film preparation. This appearance is characteristic of lymphocytes so damaged. Three plasmacytoid lymphocytes with abundant cytoplasm and a deeper blue cytoplasmic staining are present. A normal band neutrophil is present and a swollen band neutrophil that has been damaged in film preparation is evident on the left side of the image.

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V.I.004

Plasma cell. Marrow film. Characteristic plasma cell. Large oval cell. Deep blue cytoplasm. Eccentric nucleus, large distinct paranuclear clear zone.

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V.I.005

Plasma cell. Marrow film. Three typical plasma cells. Two are larger oval cells with abundant deep blue cytoplasm, an eccentric nucleus, and large paranuclear clear zones. The third is a smaller binucleate plasma cell in upper right with two eccentric nuclei and a central paranuclear clear zone. A plasma cell also is partially present at the lower edge of the image. Its cytoplasm is paler but has oval shape, eccentric nucleus, and paranuclear clear zone.

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V.I.006

Plasma cell. Marrow film. Two plasma cells. Large oval cells (one very large) with deep blue cytoplasm, an eccentric nucleus, and a large distinct paranuclear clear zone. Note the range of plasma cell size variation.

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V.I.007

Plasma cell. Marrow film. (A) Two plasma cells. Oval cells (one very large) with deep blue cytoplasm, an eccentric nucleus, and a large distinct paranuclear clear zone. Note the range of plasma cell size variation. (B) Plasma cell with a few small cytoplasmic vacules.