Sections View Full Chapter Figures Tables Videos Annotate Full Chapter Figures Tables Videos Supplementary Content +++ V.J.001 Breast Carcinoma ++ Graphic Jump LocationView Full Size||Download Slide (.ppt) V.J.001 Metastatic breast carcinoma. Marrow film. Cluster of breast carcinoma cells. +++ V.J.002 Breast Carcinoma ++ Graphic Jump LocationView Full Size||Download Slide (.ppt) V.J.002 Breast Carcinoma. Metastatic breast carcinoma. Marrow biopsy. This marrow biopsy shows poorly differentiated metastatic breast carcinoma from a patient with a history of infiltrating lobular carcinoma. Superficially, these tumor cells resemble plasma cells. +++ V.J.003 Breast Carcinoma ++ Graphic Jump LocationView Full Size||Download Slide (.ppt) V.J.003 Metastatic Breast Carcinoma Cells. (A) Marrow concentrate film. Note large cells with very large nuclei and heavily vacuolated cytoplasm. (B) Marrow biopsy. Cluster of large cells with very large nuclei and bold nucleoli. Vacuolated cytoplasm around the nuclear outlines. +++ V.J.004 Breast Carcinoma, CD138 Stain ++ Graphic Jump LocationView Full Size||Download Slide (.ppt) V.J.004 Metastatic breast cancer, CD138 stain. Marrow biopsy. CD138 (syndecan-1) stain. Although more often associated with plasma cells, CD138 expression can also be expressed by carcinoma cells. The tumor cells shown also stained for cytokeratin. No detectable kappa or lambda light chain expression was present on in situ hybridization studies. +++ V.J.005 Breast Carcinoma, Cytokeratin Stain ++ Graphic Jump LocationView Full Size||Download Slide (.ppt) V.J.005 Metastatic breast cancer, cytokeratin stain. Cytokeratin immunohistochemistry stain on same marrow shown in Figure V.J.004 confirms that the tumor seen is metastatic carcinoma. Mixture of high and low molecular weight (AE-1/3 and Cam5.2) anticytokeratin antibodies was used, stained by standard peroxidase-antiperoxidase technique using 3-amino-9-ethylcarbazole substrate. +++ V.J.006 Ewing Sarcoma ++ Graphic Jump LocationView Full Size||Download Slide (.ppt) V.J.006 Ewing Sarcoma. Marrow film. Very Large Ewing sarcoma cells. Most with scant cytoplasm and one with evident large nucleolus. +++ V.J.007 Lung Carcinoma ++ Graphic Jump LocationView Full Size||Download Slide (.ppt) V.J.007 Metastatic lung carcinoma cells. Marrow film. A cluster of metastatic lung cells. +++ V.J.008 Lung Carcinoma ++ Graphic Jump LocationView Full Size||Download Slide (.ppt) V.J.008 Metastatic Lung Carcinoma Cells. Marrow Sections. (A, B) Aggregates of metastatic small cell carcinoma of the lung cells. Note large size compared to neutrophil in (B) and tendency to aggregate. +++ V.J.009 Prostate Cancer ++ Graphic Jump LocationView Full Size||Download Slide (.ppt) V.J.009 Metastatic prostatic carcinoma cells. Marrow film. A cluster of prostatic carcinoma cells. +++ V.J.010 Neuroblastoma ++ Graphic Jump LocationView Full Size||Download Slide (.ppt) V.J.010 Neuroblastoma cells. Marrow film. Note characteristic rosette formation of neuroblastoma cells. +++ V.J.011 Rhabdomyosarcoma ++ Graphic Jump LocationView Full Size||... Your MyAccess profile is currently affiliated with '[InstitutionA]' and is in the process of switching affiliations to '[InstitutionB]'. Please click ‘Continue’ to continue the affiliation switch, otherwise click ‘Cancel’ to cancel signing in. Get Free Access Through Your Institution Learn how to see if your library subscribes to McGraw Hill Medical products. Subscribe: Institutional or Individual Sign In Username Error: Please enter User Name Password Error: Please enter Password Forgot Username? Forgot Password? Sign in via OpenAthens Sign in via Shibboleth