Sections View Full Chapter Figures Tables Videos Annotate Full Chapter Figures Tables Videos Supplementary Content +++ VIII.B.001 T(1;7)(q10;q10) G-banding ++ Graphic Jump LocationView Full Size||Download Slide (.ppt) VIII.B.001 t(1;7)(q10;q10) G-banding. Arrow indicates replacement of 7q by 1q. +++ VIII.B.002 Inv(3)(q21q26) G-banding ++ Graphic Jump LocationView Full Size||Download Slide (.ppt) VIII.B.002 inv(3)(q21q26) G-banding. Arrow indicates inverted segment on long arm of chromosome 3. Note different banding pattern of lower portion of long arm compared to normal. +++ VIII.B.003 Del(5)(q13) G-banding ++ Graphic Jump LocationView Full Size||Download Slide (.ppt) VIII.B.003 del(5)(q13) G-banding. Arrow indicates loss of most of long arm. Note also other numerical and structural abnormalities (e.g., monosomy 17, 18, 21, 22, and additional chromosomes labeled “A”). +++ VIII.B.004 -5/del(5)(q13) FISH ++ Graphic Jump LocationView Full Size||Download Slide (.ppt) VIII.B.004 -5/del(5)(q13) FISH. EGR1 gene probe located on 5q31. (A) Normal cell. Note two green signals reflecting centromere probe for chromosome 5 and two red signals for the EGF1 gene on band 5q31 (interphase preparation). (B) Abnormal showing two green signals for the centromeres of the two chromosomes 5, but absence of one red signal indicating a deletion of 5q involving EGR1 gene on 5q31 (interphase preparation). +++ VIII.B.005 Monosomy 7 (-7) G-Banding ++ Graphic Jump LocationView Full Size||Download Slide (.ppt) VIII.B.005 Monosomy 7 (-7) G-banding. Arrow indicates loss of one chromosome 7. Note additional abnormality labeled “A,” which is an inverted chromosome 6 involving both the p and q arms. +++ VIII.B.006 Monosomy 7 (-7) FISH ++ Graphic Jump LocationView Full Size||Download Slide (.ppt) VIII.B.006 Monosomy 7 (-7) FISH. Probe for centromere of chromosome 7 emitting a green signal. (A) Normal cell showing signal for two chromosome 7 (interphase preparation). (B) Abnormal showing only one signal for chromosome 7 (interphase preparation). +++ VIII.B.007 Del(7)(q22) G-banding ++ Graphic Jump LocationView Full Size||Download Slide (.ppt) VIII.B.007 del(7)(q22) G-banding. Arrow indicates loss of part of long arm of chromosome 7. Note also missing Y chromosome. +++ VIII.B.008 Trisomy 8 (+8) G-banding ++ Graphic Jump LocationView Full Size||Download Slide (.ppt) VIII.B.008 Trisomy 8 (+8) G-banding. Arrow indicates additional chromosome 8. +++ VIII.B.009 Trisomy 8 (+8) FISH ++ Graphic Jump LocationView Full Size||Download Slide (.ppt) VIII.B.009 Trisomy 8 (+8) FISH. Probe for centromere of chromosome 8 emitting green signal. (A) Normal cell. Note two signals in nucleus representing pair of chromosome 8. (interphase preparation). (B) Note three interphase nuclei emitting three signals in each nucleus, representing trisomy 8 (interphase preparation). +++ VIII.B.010 T(8;21)(q22;q22) G-banding ++ Graphic Jump LocationView Full Size||Download Slide (.ppt) VIII.B.010 t(8;21)(q22;q22) G-banding. Arrows at chromosomes 8 and 21 ... Your Access profile is currently affiliated with '[InstitutionA]' and is in the process of switching affiliations to '[InstitutionB]'. Please click ‘Continue’ to continue the affiliation switch, otherwise click ‘Cancel’ to cancel signing in. Get Free Access Through Your Institution Learn how to see if your library subscribes to McGraw Hill Medical products. Subscribe: Institutional or Individual Sign In Username Error: Please enter User Name Password Error: Please enter Password Forgot Password? Forgot Username? Sign in via OpenAthens Sign in via Shibboleth