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Numbers in brackets refer to the chapter(s) written or co-written by the contributor.

James L. Abbruzzese, MD

Chief, Division of Medical Oncology,

Department of Medicine; Associate Director,

Clinical Research, Duke Cancer Institute,

Durham, North Carolina [49]

John W. Adamson, MD

Clinical Professor,

Division of Hematology/Oncology,

Department of Medicine,

University of California at San Diego,

San Diego, California [2, 7]

Kenneth C. Anderson, MD

Kraft Family Professor of Medicine,

Harvard Medical School;

Chief, Jerome Lipper Multiple Myeloma Center,

Dana-Farber Cancer Institute,

Boston, Massachusetts [12, 18]

Frederick R. Appelbaum, MD

Director, Division of Clinical Research,

Fred Hutchinson Cancer Research Center,

Seattle, Washington [31]

Valder R. Arruda, MD, PhD

Associate Professor,

Division of Hematology,

Department of Pediatrics,

Perelman School of Medicine,

University of Pennsylvania,

Philadelphia, Pennsylvania [21]

Robert S. Benjamin, MD

P. H. and Faye E. Robinson Distinguished Professor of Medicine,

Department of Sarcoma Medical Oncology,

The University of Texas M.D. Anderson Cancer Center,

Houston, Texas [47]

Edward J. Benz, Jr., MD

Richard and Susan Smith Professor of Medicine;

Professor of Genetics, Harvard Medical School;

President and CEO, Dana-Farber Cancer Institute;

Director and Principal Investigator,

Dana-Farber/Harvard Cancer Center;

Boston, Massachusetts [8]

John L. Berk, MD

Associate Professor of Medicine,

Boston University School of Medicine;

Clinical Director, Amyloidosis Center,

Boston Medical Center,

Boston, Massachusetts [19]

Clara D. Bloomfield, MD

Distinguished University Professor;

William G. Pace, III Professor of Cancer Research;

Cancer Scholar and Senior Advisor,

The Ohio State University Comprehensive Cancer Center;

Arthur G. James Cancer Hospital and Richard J. Solove Research Institute,

Columbus, Ohio [14]

George J. Bosl, MD

Professor of Medicine,

Weill Cornell Medical College;

Chair, Department of Medicine;

Patrick M. Byrne Chair in Clinical Oncology,

Memorial Sloan-Kettering Cancer Center,

New York, New York [45]

Otis W. Brawley, MD, FACP

Professor of Hematology,

Medical Oncology, Medicine and Epidemiology,

Emory University; Chief Medical and Scientific Officer,

American Cancer Society, Atlanta, Georgia [28]

Cynthia D. Brown, MD

Associate Professor of Clinical Medicine,

Division of Pulmonary, Critical Care,

Sleep and Occupational Medicine Indiana University,

Indianapolis, Indiana [Review and Self-Assessment]

Brian I. Carr, MD, PhD, FRCP

IRCCS de Bellis National Center for GI Diseases,

Castellana Grotte, BA, Italy [41]

Jeffrey W. Clark, MD

Associate Professor of Medicine,

Harvard Medical School; Medical Director,

Clinical Trials Core, Dana-Farber Harvard Cancer Center;

Massachusetts General Hospital,

Boston, Massachusetts [26]

Francis S. Collins, MD, PhD

Director, National Institutes of Health,

Bethesda, Maryland [25]

Jorge Cortes, MD

D. B. Lane Cancer Research Distinguished Professor for Leukemia Research;

Deputy Chairman; Section Chief of AML and CML,

The University of Texas M.D. Anderson Cancer Center,

Houston, Texas [15]

Jennifer M. Croswell, MD, MPH

Medical Officer,

Center for Oncology Prevention Trials Research Group,

Division of Cancer Prevention, National Cancer Institute,

Bethesda, Maryland [28]

David Cunningham, MD, MB, ChB, FRCP

Professor, Head of Gastrointestinal/Lymphoma Unit;

Director of Clinical Research,

Royal Marsden NHS Trust,

London, United Kingdom [42]

Brendan D. Curti, MD

Director, Biotherapy Program,

Robert W. Franz Cancer

Research Center,

Providence Portland Medical Center,

Portland, Oregon [34]

Josep Dalmau, MD, PhD

ICREA Professor,

Institut d'Investigació Biomèdica August

Pi i Sunyer,

University of Barcelona, Barcelona,

Spain; Adjunct

Professor, University of Pennsylvania,

Philadelphia, Pennsylvania [55]

Lisa M. DeAngelis, MD

Professor of Neurology,

Weill Cornell Medical College;

Chair, Department of Neurology,

Memorial Sloan Kettering Cancer Center,

New York, New York [48]

Janice P. Dutcher, MD

Associate Director,

Cancer Research Foundation of New York,

Chappaqua, New York; Former Professor,

New York Medical College,

Valhalla, New York [56]

Jeffrey S. Dzieczkowski, MD

Physician, St. Alphonsus Regional Medical Center;

Medical Director, Coagulation Clinic,

Saint Alphonsus Medical Group,

International Medicine and Travel Medicine,

Boise, Idaho [12]

James A. Eastham, MD

Chief, Urology Service,

Florence and Theodore Baumritter/Enid Ancell Chair of Urologic Oncology,

Department of Surgery,

Sidney Kimmel Center for Prostate and Urologic Cancers,

Memorial Sloan Kettering Cancer Center,

New York, New York [44]

Ezekiel J. Emanuel, MD, PhD

Chair, Department of Medical Ethics and Health Policy,

Levy University Professor,

Perelman School of Medicine and Wharton School,

University of Pennsylvania,

Philadelphia, Pennsylvania [33]

Darren R. Feldman, MD

Associate Professor in Medicine,

Weill Cornell Medical Center;

Assistant Attending, Genitourinary Oncology Service,

Memorial Sloan-Kettering Cancer Center,

New York, New York [45]

Robert W. Finberg, MD

Chair, Department of Medicine,

University of Massachusetts Medical School,

Worcester, Massachusetts [30]

Jane E. Freedman, MD

Professor of Medicine,

University of Massachusetts Medical School,

Worcester, Massachusetts [22]

Carl E. Freter, MD, PhD, FACP

Professor of Medicine;

Director, Division of Hematology and Oncology;

Associate Director, Cancer Center,

Saint Louis University, St. Louis, Missouri [56]

John I. Gallin, MD

Director, Clinical Center,

National Institutes of Health,

Bethesda, Maryland [5]

Samuel Z. Goldhaber, MD

Professor of Medicine,

Harvard Medical School;

Director, Thrombosis Research Group,

Brigham and Women's Hospital,

Boston, Massachusetts [23]

Michael F. Greene, MD

Professor of Obstetrics,

Gynecology and Reproductive Biology,

Harvard Medical School;

Vincent Department of Obstetrics and Gynecology,

Massachusetts General Hospital,

Boston, Massachusetts [32]

Rasim Gucalp, MD

Professor of Clinical Medicine,

Albert Einstein College of Medicine;

Associate Chairman for Educational Programs,

Department of Oncology;

Director, Hematology/Oncology Fellowship,

Montefiore Medical Center,

Bronx, New York [56]

Patrick H. Henry, MD

Clinical Adjunct Professor of Medicine,

University of Iowa,

Iowa City, Iowa [4]

Katherine A. High, MD

William H. Bennett Professor of Pediatrics,

Perelman School of Medicine,

University of Pennsylvania;

Investigator, Howard Hughes Medical Institute,

The Children's Hospital of Philadelphia,

Philadelphia, Pennsylvania [21]

A. Victor Hoffbrand, DM

Emeritus Professor of Haematology,

University College, London;

Honorary Consultant Haematologist,

Royal Free Hospital,

London, United Kingdom [9]

Steven M. Holland, MD

Chief, Laboratory of Clinical Infectious Diseases,

National Institute of Allergy and Infectious Diseases,

National Institutes of Health,

Bethesda, Maryland [5]

Leora Horn, MD, MSc

Assistant Professor,

Division of Hematology and Medical Oncology,

Vanderbilt University School of Medicine,

Nashville, Tennessee [36]

Brian Houston, MD

Division of Cardiology,

Department of Medicine,

Johns Hopkins Hospital,

Baltimore, Maryland [Review and Self-Assessment]

J. Larry Jameson, MD, PhD

Robert G. Dunlop Professor of Medicine;

Dean, Perelman School of Medicine at the University of Pennsylvania;

Executive Vice President,

University of Pennsylvania for the Health System,

Philadelphia, Pennsylvania [50, 54]

Robert T. Jensen, MD

Chief, Cell Biology Section,

National Institutes of Diabetes,

Digestive and Kidney Diseases,

National Institutes of Health,

Bethesda, Maryland [51]

David H. Johnson, MD

Donald W. Seldin Distinguished Chair in Internal Medicine;

Professor and Chairman,

Department of Internal Medicine,

University of Texas Southwestern School of Medicine,

Dallas, Texas [36]

Hagop Kantarjian, MD

Chairman, Leukemia Department;

Professor of Leukemia,

The University of Texas M.D. Anderson Cancer Center,

Houston, Texas [15]

Barbara A. Konkle, MD

Professor of Medicine, Hematology,

University of Washington; Director,

Translational Research, Puget Sound Blood Center,

Seattle, Washington [3, 20]

Barnett S. Kramer, MD, MPH, FACP

Director, Division of Cancer Prevention,

National Cancer Institute,

Bethesda, Maryland [28]

Marc E. Lippman, MD, MACP, FRCP

Kathleen and Stanley Glaser Professor,

Department of Medicine, Deputy Director,

Sylvester Comprehensive Cancer Center,

University of Miami Miller School of Medicine,

Miami, Florida [38]

Dan L. Longo, MD

Professor of Medicine,

Harvard Medical School;

Senior Physician, Brigham and Women's Hospital;

Deputy Editor, New England Journal of Medicine,

Boston, Massachusetts [1, 2, 4, 6, 16-18, 26, 27, 29, 32, 37, 53, 54, 57]

Joseph Loscalzo, MD, PhD

Hersey Professor of the Theory and Practice of Medicine,

Harvard Medical School;

Chairman, Department of Medicine;

Physician-in-Chief, Brigham and Women's Hospital,

Boston, Massachusetts [22]

Christine M. Lovly, MD, PhD

Academic, Vanderbilt Ingram Cancer Center,

Vanderbilt University School of Medicine,

Nashville, Tennessee [36]

Lucio Luzzatto, MD, FRCP, FRCPath

Professor of Hematology,

University of Genova, Genova;

Scientific Director, Istituto Toscano Tumori,

Florence, Italy [10]

Susan J. Mandel, MD, MPH

Professor of Medicine;

Associate Chief, Division of Endocrinology,

Diabetes and Metabolism, Perelman School of Medicine,

University of Pennsylvania,

Philadelphia, Pennsylvania [50]

Guido Marcucci, MD

Professor of Medicine;

John B. and Jane T. McCoy Chair in Cancer Research;

Associate Director of Translational Research,

Comprehensive Cancer Center,

The Ohio State University College of Medicine,

Columbus, Ohio [14]

Robert J. Mayer, MD

Faculty Vice President for Academic Affairs,

Dana-Farber Cancer Institute;

Stephen B. Kay Family Professor of Medicine,

Harvard Medical School,

Boston, Massachusetts [39, 40]

Pat J. Morin, PhD

Senior Director,

Scientific Review and Grants Administration,

American Association for Cancer Research,

Philadelphia, Pennsylvania [25]

Robert J. Motzer, MD

Professor of Medicine,

Joan and Sanford Weill College of Medicine of Cornell University D. Attending Physician,

Genitourinary Oncology Service,

Memorial Sloan-Kettering Cancer Center,

New York, New York [43, 45]

Nikhil C. Munshi, MD

Professor of Medicine,

Harvard Medical School;

Boston VA Healthcare System;

Director of Basic and Correlative Sciences;

Associate Director, Jerome Lipper Myeloma Center,

Dana-Farber Cancer Institute,

Boston, Massachusetts [18]

Hartmut P. H. Neumann, MD

Universitaet Freiburg,

Medizinische Universitaetsklinik,

Freiburg im Breisgau, Germany [53]

Shreyaskumar R. Patel, MD

Robert R. Herring

Distinguished Professor of Medicine;

Center Medical Director,

Sarcoma Center,

The University of Texas M.D. Anderson Cancer Center,

Houston, Texas [47]

Jonathan E. Rosenberg, MD

Associate Attending;

Section Chief, Non-Prostate Program,

Division of Solid Tumor Oncology,

Department of Medicine,

Memorial Sloan-Kettering Cancer Center,

New York, New York [43]

Myrna R. Rosenfeld, MD, PhD

Department of Neurology,

Hospital Clínic/IDIBAPS,

Barcelona, Spain [55]

Edward A. Sausville, MD, PhD

Professor of Medicine,

University of Maryland School of Medicine;

Associate Director for Clinical Research,

Marlene and Stewart Greenbaum Cancer Center,

Baltimore, Maryland [29]

David T. Scadden, MD

Gerald and Darlene Professor of Medicine;

Co-Chair, Harvard Stem Cell Institute;

Co-chair, Department of Stem Cell and Regenerative Biology,

Harvard Medical School;

Director, Center for Regenerative Medicine;

Chief, Hematologic Malignancies, Cancer Center,

Massachusetts General Hospital, Boston, Massachusetts [1]

Howard I. Scher, MD

Professor of Medicine,

Joan and Sanford Weill College of Medicine of Cornell University;

D. Wayne Calloway Chair in Urologic Oncology;

Attending Physician and Chief, Genitourinary Oncology Service,

Department of Medicine,

Memorial Sloan-Kettering Cancer Center,

New York, New York [43, 44]

Michael V. Seiden, MD, PhD

Chief Medical Officer,

McKesson Specialty Health,

The Woodlands, Texas [46]

David C. Seldin, MD, PhD

Professor, Departments of Medicine and Microbiology;

Chief, Section of Hematology-Oncology;

Director, Amyloidosis Center,

Boston University School of Medicine;

Boston Medical Center,

Boston, Massachusetts [19]

Elizabeth Smyth, MB BAO, MSc

Department of Gastrointestinal Oncology,

Royal Marsden NHS Foundation Trust,

London and Sutton, United Kingdom [42]

Jerry L. Spivak, MD

Professor of Medicine and Oncology,

Hematology Division,

Johns Hopkins University School of Medicine,

Baltimore, Maryland [13]

Ayalew Tefferi, MD

Professor of Medicine and Hematology,

Mayo Clinic, Rochester, Minnesota [17]

Rajesh V. Thakker, MD, FMedSci, FR

May Professor of Medicine,

Academic Endocrine Unit,

University of Oxford; O.C.D.E.M.,

Churchill Hospital, Headington, Oxford, United Kingdom [52]

Jeffrey M. Trent, PhD, FACMG

President and Research Director,

Translational Genomics Research Institute,

Phoenix, Arizona;

Van Andel Research Institute,

Grand Rapids, Michigan [25]

Walter J. Urba, MD, PhD

Director of Research,

Earle A. Chiles Research Institute,

Providence Cancer Center, Portland, Oregon [34]

Gauri R. Varadhachary, MD

Professor,

Department of Gastrointestinal Medical Oncology,

The University of Texas M.D. Anderson Cancer Center,

Houston, Texas [49]

Bert Vogelstein, MD

Investigator, Howard Hughes Medical Institute;

Director, Ludwig Center at the Sidney Kimmel Comprehensive Cancer Center;

Clayton Professor of Oncology and Pathology;

Johns Hopkins Medical Institutions,

Baltimore, Maryland [25]

Everett E. Vokes, MD

John E. Ultmann Professor;

Chairman, Department of Medicine;

Physician-in-Chief, University of Chicago Medical Center,

Chicago, Illinois [35]

Anthony P. Weetman, MD, DSc

University of Sheffield,

School of Medicine Sheffield,

United Kingdom [50]

Jeffrey I. Weitz, MD, FRCP(C), FACP

Professor of Medicine and Biochemistry,

McMaster University; Executive Director,

Thrombosis and Atherosclerosis Research Institute,

Hamilton, Ontario, Canada [24]

Patrick Y. Wen, MD

Professor of Neurology,

Harvard Medical School; Director,

Center for Neuro-Oncology, Dana-Farber Cancer Institute;

Director, Division of Neuro-Oncology, Department of Neurology,

Brigham and Women's Hospital;

Dana-Farber Cancer Institute, Boston, Massachusetts [48]

Charles M. Wiener, MD

Vice President of Academic Affairs,

Johns Hopkins Medicine International,

Professor of Medicine and Physiology,

Johns Hopkins School of Medicine,

Baltimore, Maryland [Review and Self-Assessment]

Neal S. Young, MD

Chief, Hematology Branch,

National Heart, Lung and Blood Institute;

Director, NIH Center for Human Immunology,

Autoimmunity and Inflammation,

National Institutes of Health,

Bethesda, Maryland [11]

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