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Acknowledgements
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We should like to thank Mr Ricardo Morilla and Dr John Swansbury, both from the Royal Marsden Hospital, who have contributed illustrations of cytogenetic analysis and flow cytometry. They are individually acknowledged in the legends to the relevant figures.

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We also wish to acknowledge, with gratitude, the leadership of Professor Daniel Catovsky and the late Professor David Galton, together with other members of the FAB group, and that of Professor John Goldman, in the field of haematological malignancy, over the last 40 years. They and other colleagues at St Mary's Hospital, Hammersmith Hospital, and the Royal Marsden Hospital have generously shared their knowledge with us.

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Barbara J Bain
Estella Matutes

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