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Abbreviations
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ACE angiotensin-converting enzyme
ADLs activities of daily living
AE adverse event
AKI acute kidney injury
ALF acute liver failure
ALP alkaline phosphatase
ALT alanine transaminase
AOS acute oncology service(s)
AOT acute oncology team
AR adverse reaction
ASCO American Society of Clinical Oncology
AST aspartate transaminase
bpm beats per minute
BCNU bis-chloroethylnitrosourea (carmustine)
CA125 cancer antigen 125 (MUC16, mucin 16)
CCC Clatterbridge Cancer Centre
CEA carcinoembryonic antigen
CFS cerebrospinal fluid
CHF congestive heart failure
CID chemotherapy-induced diarrhoea
CKD chronic kidney disease
CNS central nervous system
CONcePT Comparison of Oxaliplatin vs Conventional Methods with Calcium/Magnesium in First-Line Metastatic Colorectal Cancer (NCT00129870)
COPD chronic obstructive pulmonary disease
COSA Clinical Oncology Society of Australia
CPAP continuous positive airway pressure
Cr creatinine
CRF case record form
CT computed tomography
CTCAE Common Terminology Criteria for Adverse Events
CUP cancer of unknown primary
CVP central venous pressure
DGH district general hospital
DM diabetes mellitus
DPP-4 dipeptidyl peptidase 4
DPYD dihydropyrimidine dehydrogenase
DVT deep vein thrombosis
EC epirubicin and cyclophosphamide
ECG electrocardiogram
ECOG Eastern Cooperative Oncology Group
ED emergency department
EDTA ethylenediaminetetraacetic acid
EGFR epidermal growth factor receptor
FBC full blood count
FEC fluorouracil, epirubicin and cyclophosphamide
5-FU fluorouracil
FNA fine-needle aspiration
GCP good clinical practice
G-CSF granulocyte colony-stimulating factor
GEBP gene expression-based profiling
GFR glomerular filtration rate
GI gastrointestinal
GIST gastrointestinal stromal tumour
GLP-1 glucagon-like peptide-1
GP general practitioner
Hb haemoglobin concentration
HbA1c glycosylated haemoglobin
HBcAg core antigen of hepatitis B virus
HBeAg core antigen of hepatitis B virus, extracellular form
HBsAg surface antigen of hepatitis B virus
HBV hepatitis B virus
HER2 human epidermal growth factor receptor 2
HFS hand-foot syndrome
HSCT haematopoietic stem cell transplantation
IB Investigator Brochure
IDSA Infectious Diseases Society of America
IgE immunoglobulin E
IMRT intensity-modulated radiation therapy
INR international normalized ratio
IV intravenous
IVC inferior vena cava
LEVF left ventricular ejection fraction
LMWH low-molecular-weight heparin
LN lymph node
MASCC Multinational Association of Supportive Care in Cancer
MCCN Merseyside and Cheshire Cancer Network
MdG modified de Gramont regimen
MDT multi disciplinary team
MOSAIC Multicenter International Study of Oxaliplatin/5FU-LV in the Adjuvant Treatment of Colon Cancer
MRCC metastatic renal cell carcinoma
MRI magnetic resonance imaging
MRSA methicillin-resistant Staphylococcus aureus
MSCC metastatic spinal cord compression
MUO malignancy of undefined primary origin
NCAG National Cancer Action Group
NCCTG North Central Cancer Treatment Group
NCEPOD National Confidential Enquiry into Patient Outcome and Death
NCIN National Cancer Intelligence Network
NCQA National Committee for Quality Assurance
NEWS national early warning score
NHS National Health Service
NICE National Institute for Health and Care Excellence
NNH number needed to harm
NNT number needed to treat
NS neutropenic sepsis
NYHA New York Heart Association
OPD outpatient department
PCD paraneoplastic cerebellar degeneration
PCN percutaneous nephrostomy
PDGF platelet-derived growth factor
PDGFR PDGF receptor
PE pulmonary embolus
PET positron emission tomography
PICC peripherally inserted central catheter
PIS patient information sheet
PO2 oxygen tension (partial pressure)
PPI proton pump inhibitor
PQRI Physician Quality Reporting Initiative
PRES posterior reversible encephalopathy syndrome
PSA prostate-specific antigen
PTHrP parathyroid hormone-related protein
QOPI Quality of Oncology Practice Initiative
RCP Royal College of Physicians
RPA recursive partitioning analysis
RTK receptor tyrosine kinase
RTOG Radiation Therapy Oncology Group
RUL right upper lobe
SAAG serum-ascites albumin gradient
SACT systemic anticancer therapy
SAE serious adverse event
SAR serious adverse reaction
SCF supraclavicular fossa
SCLC small-cell lung cancer
SIADH syndrome of inappropriate antidiuretic hormone
SJIO St James's Institute of Oncology
SpO2 arterial oxygen saturation measured by pulse oximetry
SpR specialist registrar
SRS stereotactic radiosurgery
SSG site-specific group
SUSAR suspected unexpected serious adverse reaction
SVCO superior vena cava obstruction
T4 levothyroxine
TKI tyrosine kinase inhibitor
TLS tumour lysis syndrome
U&Es blood test for urea and electrolytes (sodium and potassium)
UGT uridine diphosphate-glucuronosyltransferase
UK United Kingdom
Ur supraclavicular fossa
US United States (of America)
VATS video-assisted thoracic surgery
VEGF vascular endothelial growth factor
VEGFR VEGF receptor
VRE vancomycin-resistant Enterococcus
VTE venous thromboembolism
WBC white blood cell count
WBRT whole-brain radiotherapy
WHO World Health Organization

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