Sections View Full Chapter Figures Tables Videos Annotate Full Chapter Figures Tables Videos Supplementary Content ++ Laboratory Variables Relevant to Hematologic Diagnosis (Normal Adult Values) ++ Table Graphic Jump Location|Download (.pdf)|Print BLOOD CELLS Variable (Common Abbreviations) Units Values Hematocrit (HCT) or packed cell volume (PCV) mL red cells/dL blood or percent M = 42–51a F = 36–46a Hemoglobin (Hb, Hgb) g/L blood M = 140–180a F = 120–150a Red cell count (RBC, RCC) 1012/L M = 4.5–6.0a F = 4.1–5.1a Mean cell volume (MCV) fL/cell M = 80–96 F = 79–94 Mean cell hemoglobin (MCH) pg/cell 27–33 Mean cell hemoglobin concentration (MCHC) g/dL red cells 33–36 Red cell distribution width (RDW) Percent <15 Reticulocyte count, relative Percent of red cells 0.5–1.5 Reticulocyte count, absolute 109/L 50–100b Reticulocyte hemoglobin (CHr) pg/cell 27–33 Total blood volume (TBV)c,d mL/kg M = 80 (54–108) F = 71 (41–105) Plasma volume (PV)c,d mL/kg M = 45 (27–61) F = 43 (26–69) Red cell mass (RCM)c,d mL/kg M = 35 (20–51) F = 28 (15–41) Platelet count 109/L 175–450 White cell count (WBC, WCC) 109/L 4.8–10.8 Absolute monocyte count 109/L 0.3–0.8 Absolute neutrophil count 109/L 1.8–7.7 Absolute lymphocyte count 109/L 1.0–4.8 CD3-positive lymphocytes 109/L 0.7–1.9 CD4-positive lymphocytes 109/L 0.4–1.4 CD8-positive lymphocytes 109/L 0.2–0.7 CD19-positive lymphocytes 109/L 0.050–0.375 HEMOGLOBIN ELECTROPHORESISe Hemoglobin A1 Percent of total hemoglobin 96.1–99.0 Hemoglobin A2 Percent of total hemoglobin 0.8–3.4 Hemoglobin F Percent of total hemoglobin 0.0–1.2 COAGULATION TESTS Prothrombin time (PT) Seconds to clot 12–14f International normalized ratio (INR) Unitless 0.8–1.2 Partial thromboplastin time (PTT) Seconds to clot 19–30f Thrombin time Seconds to clot 10–15 Closure time (PFA-100) collagen/epinephrine (CEPI) Seconds <175 Clot retraction Percent in 1 hour >40 Fibrinogen mg/dL 188–381 D-dimer ng/mL <400g Factor II, V, and VII Percent of normal mean 50–150 Factor VIII:C activity Percent of normal mean 50–200 Willebrand factor activity Percent of normal mean 60–200h Willebrand factor antigen Percent of normal mean mg/L 50–160h ~100 Factor VIII inhibitor Bethesda units 0–0.5 Factor IX Percent of normal mean mg/L 50–150 ~4.0 Factor X Percent of normal mean mg/L 50–150 ~10 Factor XI Percent of normal mean mg/L 50–150 ~7.0 Factor XII Percent of normal mean 50–150 Factor XIII Percent of normal mean 70–130 α2-Antiplasmin Percent of normal mean 80–120 Plasminogen Percent of normal mean 80–120 Antithrombin: Functional assay Immunologic assay Percent of normal mean mg/dL 80–120 22–33 Protein C Percent of normal mean μg/mL 70–140 3.0–5.0 Activated protein C (APC) resistance APC ratio >1.5 Protein S Total Free Free/total ratio Percent of normal mean μg/mL μg/mL Unitless 65–140 20–25 6–10 ~0.4 Fibrin degradation products (latex particles) μg/mL <20 Platelet aggregation (in platelet-rich plasma) With collagen (2 μg/mL) With arachidonic acid (0.5 mM) With ADP 5 μM With ADP 10 μM With epinephrine (5 μM) With ristocetin (1.0 mg/mL) Percent of ... Your Access profile is currently affiliated with [InstitutionA] and is in the process of switching affiliations to [InstitutionB]. Please select how you would like to proceed. Keep the current affiliation with [InstitutionA] and continue with the Access profile sign in process Switch affiliation to [InstitutionB] and continue with the Access profile sign in process Get Free Access Through Your Institution Learn how to see if your library subscribes to McGraw Hill Medical products. Subscribe: Institutional or Individual Sign In Error: Incorrect UserName or Password Username Error: Please enter User Name Password Error: Please enter Password Sign in Forgot Password? Forgot Username? Sign in via OpenAthens Sign in via Shibboleth You already have access! Please proceed to your institution's subscription. Create a free profile for additional features.