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Laboratory Variables Relevant to Hematologic Diagnosis (Normal Adult Values)

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BLOOD CELLS
Variable (Common Abbreviations) Units Values
Hematocrit (HCT) or packed cell volume (PCV) mL red cells/dL blood or percent

M = 42–51a

F = 36–46a

Hemoglobin (Hb, Hgb) g/L blood

M = 140–180a

F = 120–150a

Red cell count (RBC, RCC) 1012/L

M = 4.5–6.0a

F = 4.1–5.1a

Mean cell volume (MCV) fL/cell

M = 80–96

F = 79–94

Mean cell hemoglobin (MCH) pg/cell 27–33
Mean cell hemoglobin concentration (MCHC) g/dL red cells 33–36
Red cell distribution width (RDW) Percent <15
Reticulocyte count, relative Percent of red cells 0.5–1.5
Reticulocyte count, absolute 109/L 50–100b
Reticulocyte hemoglobin (CHr) pg/cell 27–33
Total blood volume (TBV)c,d mL/kg

M = 80 (54–108)

F = 71 (41–105)

Plasma volume (PV)c,d mL/kg

M = 45 (27–61)

F = 43 (26–69)

Red cell mass (RCM)c,d mL/kg

M = 35 (20–51)

F = 28 (15–41)

Platelet count 109/L 175–450
White cell count (WBC, WCC) 109/L 4.8–10.8
Absolute monocyte count 109/L 0.3–0.8
Absolute neutrophil count 109/L 1.8–7.7
Absolute lymphocyte count 109/L 1.0–4.8
CD3-positive lymphocytes 109/L 0.7–1.9
CD4-positive lymphocytes 109/L 0.4–1.4
CD8-positive lymphocytes 109/L 0.2–0.7
CD19-positive lymphocytes 109/L 0.050–0.375
HEMOGLOBIN ELECTROPHORESISe
Hemoglobin A1 Percent of total hemoglobin 96.1–99.0
Hemoglobin A2 Percent of total hemoglobin 0.8–3.4
Hemoglobin F Percent of total hemoglobin 0.0–1.2
COAGULATION TESTS
Prothrombin time (PT) Seconds to clot 12–14f
International normalized ratio (INR) Unitless 0.8–1.2
Partial thromboplastin time (PTT) Seconds to clot 19–30f
Thrombin time Seconds to clot 10–15
Closure time (PFA-100) collagen/epinephrine (CEPI) Seconds <175
Clot retraction Percent in 1 hour >40
Fibrinogen mg/dL 188–381
D-dimer ng/mL <400g
Factor II, V, and VII Percent of normal mean 50–150
Factor VIII:C activity Percent of normal mean 50–200
Willebrand factor activity Percent of normal mean 60–200h
Willebrand factor antigen

Percent of normal mean

mg/L

50–160h

~100

Factor VIII inhibitor Bethesda units 0–0.5
Factor IX

Percent of normal mean

mg/L

50–150

~4.0

Factor X

Percent of normal mean

mg/L

50–150

~10

Factor XI

Percent of normal mean

mg/L

50–150

~7.0

Factor XII Percent of normal mean 50–150
Factor XIII Percent of normal mean 70–130
α2-Antiplasmin Percent of normal mean 80–120
Plasminogen Percent of normal mean 80–120

Antithrombin:

 Functional assay

 Immunologic assay

 

Percent of normal mean

mg/dL

 

80–120

22–33

Protein C

Percent of normal mean

μg/mL

70–140

3.0–5.0

Activated protein C (APC) resistance APC ratio >1.5

Protein S

 Total

 Free

 Free/total ratio

Percent of normal mean

μg/mL

μg/mL

Unitless

65–140

20–25

6–10

~0.4

Fibrin degradation products (latex particles) μg/mL <20

Platelet aggregation (in platelet-rich plasma)

 With collagen (2 μg/mL)

 With arachidonic acid (0.5 mM)

 With ADP 5 μM

 With ADP 10 μM

 With epinephrine (5 μM)

 With ristocetin (1.0 mg/mL)

 

Percent of ...

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