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Laboratory Variables Relevant to Hematologic Diagnosis (Normal Adult Values)

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BLOOD CELLS

Variable (Common Abbreviations)

Units

Values

Hematocrit (HCT) or Packed cell volume (PCV)

Percent or mL red cells/dL blood, respectively

M = 42–51

F = 36–46

Hemoglobin (Hb, Hgb)

g/dL blood

M = 14–18

F = 12–15

Red cell count (RBC, RCC)

106/μL or 1012/L

M = 4.5–6.0

F = 4.1–5.1

Mean cell volume (MCV)

fL/cell

M = 80–96

F = 79–94

Mean cell hemoglobin (MCH)

pg/cell

27–33

Mean cell hemoglobin concentration (MCHC)

g/dL red cells

33–36

Red cell distribution width (RDW)

Percent

< 15

Reticulocyte count

Percent of red cells

0.5–1.5

Reticulocyte hemoglobin (CHr)

pg/cell

27–33

Total blood volume (TBV)

mL/kg

65–85+; 55–75#

Plasma volume (PV)

mL/kg

39–44

Red cell mass (RCM)

mL/kg

25–35

Platelet count

103/μL or 109/L

175–450

White cell count (WBC, WCC)

103/μL or 109/L

4.8–10.8

Absolute monocyte count

103/μL or 109/L

0.3–0.8

Absolute neutrophil count

103/μL or 109/L

1.8–7.7

Absolute lymphocyte count

103/μL or 109/L

1.0–4.8

CD3-positive lymphocytes

103/μL or 109/L

700–1900

CD4-positive lymphocytes

103/μL or 109/L

400–1400

CD8-positive lymphocytes

103/μL or 109/L

200–700

CD19-positive lymphocytes

103/μL or 109/L

50–375

HEMOGLOBIN ELECTROPHORESIS*

Hemoglobin A1

Percent of total hemoglobin

96.1–99.0

Hemoglobin A2

Percent of total hemoglobin

0.8–3.4

Hemoglobin F

Percent of total hemoglobin

0.0–1.2

COAGULATION TESTS

Prothrombin time (PT)

Seconds to clot

12–14

International Normalized Ratio (INR)

None

0.8-1.2

Partial thromboplastin time (PTT)

Seconds to clot

19–30

Thrombin time

Seconds to clot

10–15

Closure time (PFA-100) Collagen/epinephrine (CEPI)

Seconds

<175

Clot retraction

Percent in 1 hour

>40

Fibrinogen

mg/dL plasma

188–381

D-Dimer

ng/mL

<400

Factor II, V, and VII

Percent of normal mean

50–150

Factor VIII: c activity

Percent of normal mean

50–200

Willebrand factor activity

Percent of normal mean

60–200§

Willebrand factor antigen

Percent of normal mean

mg/L

50–160§

~ 100

Factor VIII-inhibitor

Bethesda units

0–0.5

Factor IX

Percent of normal mean

Mg/L

50–150

~ 4.0

Factor X

Percent of normal mean

mg/L

50–150

~ 10

Factor XI

Percent of normal mean

mg/L

50–150

~ 7.0

Factor XII

Percent of normal mean

50–150

Factor XIII

Percent of normal mean

70–130

α2- antiplasmin

Percent of normal mean

80–120

Plasminogen

Percent of normal mean

80–120

Antithrombin:

 Functional assay

 Immunologic assay

 

Percent of normal mean

mg/dL

 

80–120

22–33

Protein C

Percent of normal mean

μg/mL

70–140

3.0–5.0

Activated protein C resistance

APC ratio

>1.5

Protein S

 Total

 Free

 Free/total ratio

Percent of normal mean

μg/mL

μg/mL

Unitless

65–140

20–25

6–10

~ 0.4

Fibrin degradation products (latex particles)

μg/mL

<20

Platelet Aggregation (in platelet-rich plasma)

 With collagen (2 μg/mL)

 With arachidonic acid (0.5 mM)

 With ADP 5 μM

 With ADP 10 μM

 With epinephrine (5 ...

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