TY - CHAP M1 - Book, Section TI - Abnormal Erythroid Precursor Cells A1 - MA, Lichtman A1 - MS, Shafer A1 - RE, Felgar A1 - N, Wang PY - 2017 T2 - Lichtman's Atlas of Hematology 2016 AB - Graphic Jump LocationView Full Size||Download Slide (.ppt)V.G.001Alcohol poisoning. Marrow cells of a patient with chronic and acute alcoholism. Note dyserythropoiesis. Small erythroblasts with scant cytoplasm. Large orthochromatic erythroblast with lobulated nucleus. Three large erythroblasts (one proerythroblast and two basophilic erythroblasts) with vacuoles characteristic (but not specific for) of acute alcoholism. The vacuoles usually occur in early erythroid cells as seen here and very occasionally in myeloid cells. They may be observed after abstinence for about 3 to 14 days, suggesting the vacuoles persist that long despite cell division and maturation. The vacuoles often appear to overlie the nucleus as well as the cytoplasm, but in electron micrographic studies, they form from endocytotic vesicles and are localized only to the cytoplasm. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/03/28 UR - hemonc.mhmedical.com/content.aspx?aid=1138037815 ER -