TY - CHAP M1 - Book, Section TI - Antiviral Agents (Nonretroviral) A1 - Hilal-Dandan, Randa A1 - Brunton, Laurence L. PY - 2016 T2 - Goodman and Gilman's Manual of Pharmacology and Therapeutics, 2e AB - Viruses are simple microorganisms that consist of either double- or single-stranded DNA or RNA enclosed in a protein coat called a capsid. Some viruses also possess a lipid envelope derived from the infected host cell, which, like the capsid, may contain antigenic glycoproteins. Effective antiviral agents inhibit virus-specific replicative events or preferentially inhibit virus-directed rather than host cell–directed nucleic acid or protein synthesis (Table 58-1). Host cell molecules that are essential to viral replication also offer targets for intervention. Figure 58-1 gives a schematic diagram of the replicative cycle of typical DNA and RNA viruses. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/10/09 UR - hemonc.mhmedical.com/content.aspx?aid=1127554293 ER -