TY - CHAP M1 - Book, Section TI - Immunology of Hematopoietic Stem Cell Transplantation A1 - Viswanathan, Srinivas A1 - Chen, Yi-Bin A2 - Chabner, Bruce A. A2 - Longo, Dan L. PY - 2016 T2 - Harrison's Manual of Oncology, 2e AB - Hematopoietic stem cell transplantation (HSCT) has wide applications in the treatment of hematologic malignancies, congenital and acquired disorders of hematopoiesis, and autoimmune disease. Transplanted hematopoietic progenitors can reconstitute the full spectrum of hematopoietic cells in a recipient host, and can also confer immunologic antitumor activity. HSCT is therefore employed for both cellular replacement and for cancer immunotherapy. This chapter reviews the basic immunology of HSCT. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/04/24 UR - hemonc.mhmedical.com/content.aspx?aid=1127648418 ER -