TY - CHAP M1 - Book, Section TI - The Thalassemias A1 - Lichtman, Marshall A. A1 - Kaushansky, Kenneth A1 - Prchal, Josef T. A1 - Levi, Marcel M. A1 - Burns, Linda J. A1 - Armitage, James O. PY - 2017 T2 - Williams Manual of Hematology, 9e AB - Each of these disorders results from an inherited defect in the rate of synthesis of one or another of globin chains.Resultant imbalance of globin chain production may cause ineffective erythropoiesis, defective hemoglobin production, red cell hemoglobin precipitates, hemolysis, anemia of variable degree and propensity to iron overload. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/04/25 UR - hemonc.mhmedical.com/content.aspx?aid=1133362823 ER -