TY - CHAP M1 - Book, Section TI - Drug-Induced Hemolytic Anemia A1 - Lichtman, Marshall A. A1 - Kaushansky, Kenneth A1 - Prchal, Josef T. A1 - Levi, Marcel M. A1 - Burns, Linda J. A1 - Armitage, James O. PY - 2017 T2 - Williams Manual of Hematology, 9e AB - Three mechanisms of drug-related immunologic injury to red cells are defined:— Hapten/drug adsorption involving drug-dependent antibodies— Ternary complex formation involving drug-dependent antibodies— Induction of autoantibodies that react with red cells in the absence of the inciting drugDrug-related nonimmunologic protein adsorption may also result in a positive direct antiglobulin test without red cell injury.Table 24–1 lists the drugs implicated in the production of a positive direct antiglobulin test and accelerated red cell destruction.Table 24–2 summarizes the four mechanisms of drug-induced immune interaction with the red cell surface. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/10/09 UR - hemonc.mhmedical.com/content.aspx?aid=1133363131 ER -