TY  - CHAP
M1  - Book, Section
TI  - Polyclonal Polycythemias (Primary and Secondary)
A1  - Lichtman, Marshall A.
A1  - Kaushansky, Kenneth
A1  - Prchal, Josef T.
A1  - Levi, Marcel M.
A1  - Burns, Linda J.
A1  - Armitage, James O.
PY  - 2017
T2  - Williams Manual of Hematology, 9e
AB  - Polycythemia,  also  referred  to  as  erythrocytosis,  is  characterized  by  an  increased  red  cell  mass.  There  is  no  consensus  on  terminology  (ie,  primary  familial  polycythemia  but  postrenal  transplantation  erythrocytosis).  Polycythemias  can  be  primary  or  secondary  and  can  be  inherited  or  acquired.Classification  of  polycythemic  disorders  appears  in  Table  2–2  in  Chap.  2.Primary  polycythemias  are  caused  by  somatic  or  germline  mutations  within  hematopoietic  stem  cells  or  erythroid  progenitors  that  result  in  an  augmented  response  to  erythropoietin.  This  response  is  inappropriate;  that  is,  it  is  not  a  compensation  for  hypoxia.Secondary  polycythemias  are  caused  by  either  an  appropriate  (compensatory)  or  inappropriate  increase  in  the  red  cell  mass  as  a  result  of  augmented  levels  of  erythropoietin.  
SN  - 
PB  - McGraw-Hill Education
CY  - New York, NY
Y2  - 2024/04/20
UR  - hemonc.mhmedical.com/content.aspx?aid=1133363268
ER  -