TY - CHAP M1 - Book, Section TI - Classification and Clinical Manifestations of Monocytes and Macrophages A1 - Lichtman, Marshall A. A1 - Kaushansky, Kenneth A1 - Prchal, Josef T. A1 - Levi, Marcel M. A1 - Burns, Linda J. A1 - Armitage, James O. PY - 2017 T2 - Williams Manual of Hematology, 9e AB - Classification is difficult because few diseases result solely in disturbance of monocytes.Presence of monocytosis, monocytopenia, or histiocytosis may be an important diagnostic feature and may contribute to functional abnormalities.The terms “macrophage” and “histiocyte” are synonymous.— Macrophage is the correct designation when discussing tissue disorders of the mononuclear phagocyte system.— The latter system is the sum of the marrow, blood and tissue pool of monocytes and macrophages. (The term reticuloendothelial for this system is obsolete.)— For historical reasons, macrophage disorders are referred to by pathologists as a histiocytic disorder or a histiocytosis (eg, Langerhans cell histiocytosis). SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/03/29 UR - hemonc.mhmedical.com/content.aspx?aid=1133363575 ER -