TY - CHAP M1 - Book, Section TI - Acute Myeloid Leukemia A1 - Marcucci, Guido A1 - Bloomfield, Clara D. A2 - Longo, Dan L. PY - 2016 T2 - Harrison's Hematology and Oncology, 3e AB - Acute myeloid leukemia (AML) is a neoplastic disease characterized by infiltration of the blood, bone marrow, and other tissues by proliferative, clonal undifferentiated cells of the hematopoietic system. These leukemias comprise a spectrum of malignancies that, untreated, range from rapidly fatal to slowly growing. In 2013, the estimated number of new AML cases in the United States was 14,590. The incidence of AML is ~3.5 per 100,000 people per year, and the age-adjusted incidence is higher in men than in women (4.5 vs 3.1). AML incidence increases with age; it is 1.7 in individuals age 65 years. The median age at diagnosis is 67 years. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/03/28 UR - hemonc.mhmedical.com/content.aspx?aid=1135227156 ER -