TY - CHAP M1 - Book, Section TI - Biopsy and Definitive Excision of Primary Cutaneous Melanomas A1 - Balch, Charles M. A1 - Balch, Glen C. A1 - Thompson, John F. A2 - Morita, Shane Y. A2 - Balch, Charles M. A2 - Klimberg, V. Suzanne A2 - Pawlik, Timothy M. A2 - Posner, Mitchell C. A2 - Tanabe, Kenneth K. PY - 2018 T2 - Textbook of Complex General Surgical Oncology AB - A skin lesion that is suspicious for melanoma is best removed by excisional biopsy with a 1- to 2-mm clinical lateral margin and a deep margin into the subcutaneous fat, underneath all epithelial appendageal structures.1 This can be performed on most lesions up to 1.5 cm in diameter (Fig. 13-1). The biopsy scar should be oriented to be compatible with a subsequent wide local excision should the lesion prove to be melanoma. On the extremities a longitudinal or oblique incision is preferred. On the trunk or the head and neck the biopsy should be oriented parallel to the skin lines. A full-thickness biopsy should be undertaken in order to accurately interpret the maximum tumor thickness, the presence or absence of ulceration, and the level of invasion.1 SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/04/19 UR - hemonc.mhmedical.com/content.aspx?aid=1145755839 ER -