TY - CHAP M1 - Book, Section TI - Pleural Diseases: Primary and Metastatic Malignancies A1 - Revels, Sha'Shonda L. A1 - Reddy, Rishindra M. A2 - Morita, Shane Y. A2 - Balch, Charles M. A2 - Klimberg, V. Suzanne A2 - Pawlik, Timothy M. A2 - Posner, Mitchell C. A2 - Tanabe, Kenneth K. PY - 2018 T2 - Textbook of Complex General Surgical Oncology AB - Pleural malignant disease is a heterogeneous group of cancers that range from primary intrathoracic cancers such as mesothelioma to metastatic cancers from extrathoracic sources. Often found incidentally, pleural malignancies may present as small pleural effusions or asymmetric pleural thickening on a chest x-ray or CT scan. As disease progresses, tumor may decrease lung compliance by entrapment and fluid production causing pressure on other structures, leading to symptoms of chest pain, dyspnea, and cough. Goals of care depend on the type of malignancy (primary vs. metastatic) and the ability to control disease (small volume vs. large volume). Curative treatment may be possible in early-stage primary pleural cancers or in select cases of metastatic metastases, but often palliation is the true goal for most patients with pleural disease. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/03/28 UR - hemonc.mhmedical.com/content.aspx?aid=1145759675 ER -