TY - CHAP M1 - Book, Section TI - White Blood Cell Disorders: Introduction A1 - Aster, Jon C. A1 - Bunn, H. Franklin PY - 2016 T2 - Pathophysiology of Blood Disorders, 2e AB - These drawings, showing phagocytic white blood cells (leukocytes) from various species, are those of Elie Metchnikoff, an early pioneer in the field of immunity who shared the Nobel Prize in 1908 with Paul Ehrlich, another founding father of modern immunology. Metchnikoff was the first to recognize the ability of leukocytes to move toward pathogens (chemotaxis) and subsequently surround and kill them (ideas that were highly controversial at the time). Because of their roles as both sentinels and effectors of the innate and adaptive immune system, leukocytes are frequently measured and monitored in clinical practice. An increased white blood cell count (leukocytosis) is one of the most common signs of infectious and inflammatory diseases. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/03/29 UR - hemonc.mhmedical.com/content.aspx?aid=1175525747 ER -