TY - CHAP M1 - Book, Section TI - Hereditary and Reactive Thrombocytosis A1 - Kaushansky, Kenneth A2 - Kaushansky, Kenneth A2 - Prchal, Josef T. A2 - Burns, Linda J. A2 - Lichtman, Marshall A. A2 - Levi, Marcel A2 - Linch, David C. PY - 2021 T2 - Williams Hematology, 10e AB - SUMMARYThe three major pathophysiologic causes of thrombocytosis are (1) clonal, including essential (or primary) thrombocythemia and other myeloproliferative neoplasms; (2) familial, including rare cases of nonclonal myeloproliferation resulting from thrombopoietin and thrombopoietin receptor mutations; and (3) reactive, in which thrombocytosis occurs secondary to a variety of acute and chronic clinical conditions. This chapter deals with the latter two causes of thrombocytosis. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/11/05 UR - hemonc.mhmedical.com/content.aspx?aid=1178754391 ER -