TY  - CHAP
M1  - Book, Section
TI  - Cancer Heterogeneity
A1  - Gedye, Craig
A2  - Harrington, Lea A.
A2  - Tannock, Ian F.
A2  - Hill, Richard P.
A2  - Cescon, David W.
PY  - 2021
T2  - The Basic Science of Oncology, 6e
AB  - Every  patient’s  cancer  is  different.  Cancers  arising  from  the  same  organ  may  have  different  histology  and  metastatic  potential,  may  be  indolent  or  aggressive,  and  may  have  different  response  to  therapy.  Cells  within  a  cancer  are  also  different.  Within  individual  tumors,  some  cells  are  genetically  normal  stromal  cells  and  some  are  somatically-mutated  malignant  cells.  And  within  the  malignant  cell  pool,  related  but  differently  evolved  malignant  clones  vie  for  survival,  exploiting  different  epigenetic  strategies,  within  different  microenvironments  within  each  tumor  (Fig.  13–1;  see  Chap.  12,  Sec.  12.2).  
SN  - 
PB  - McGraw-Hill Education
CY  - New York, NY
Y2  - 2024/04/16
UR  - hemonc.mhmedical.com/content.aspx?aid=1179324803
ER  -