TY - CHAP M1 - Book, Section TI - Molecular and Cellular Basis of Radiotherapy A1 - Koritzinsky, Marianne A1 - Bratman, Scott V. A2 - Harrington, Lea A. A2 - Tannock, Ian F. A2 - Hill, Richard P. A2 - Cescon, David W. PY - 2021 T2 - The Basic Science of Oncology, 6e AB - Since their discovery by Roentgen more than a century ago, x-rays have played a major role in modern medicine. The first recorded use of x-rays for the treatment of cancer occurred within 1 year of their discovery. Subsequently, there has been intensive study of x-rays and other ionizing radiations, and their clinical application to cancer treatment has become increasingly sophisticated. This chapter and Chapter 16 review the biological effects of ionizing radiation and the application of that knowledge to cancer treatment. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/03/28 UR - hemonc.mhmedical.com/content.aspx?aid=1179324987 ER -