TY  - CHAP
M1  - Book, Section
TI  - Hydroxyurea and Sickle Cell Disease
A1  - Wang, Winfred C.
A1  - Ware, Russell E.
A2  - Gladwin, Mark T.
A2  - Kato, Gregory J.
A2  - Novelli, Enrico M.
PY  - 2021
T2  - Sickle Cell Disease
AB  - Landmark  natural  history  studies,  including  the  Cooperative  Study  of  Sickle  Cell  Disease1  and  the  Jamaican  Cohort  Study,2  generated  the  seminal  observations  that  fetal  hemoglobin  (HbF)  is  a  critically  important  laboratory  parameter  for  individuals  with  sickle  cell  anemia  (SCA).  Higher  HbF  levels  are  associated  with  better  clinical  outcomes  including  reduced  mortality,3-5  and  if  present  at  sufficient  levels  with  pancellular  distribution,  higher  HbF  levels  can  lead  to  a  benign  condition.6  
SN  - 
PB  - McGraw-Hill Education
CY  - New York, NY
Y2  - 2024/04/19
UR  - hemonc.mhmedical.com/content.aspx?aid=1179345686
ER  -